Inventors:
- Oxford, GB
Forbes Dennison Porter - Bethesda MD, US
Assignee:
The Chancellor, Masters and Scholars of the University of Oxford - Oxford
The Government of the United States of America, as represented by the Secretary, Department of Healt - Bethesda MD
International Classification:
C07J 43/00, C07J 7/00, C07H 19/06, C07D 473/16, A61K 31/708, A61K 31/6615, A61K 31/661, A61K 31/675, C07H 19/20, A61K 31/7072, C07D 211/94, A61K 31/575
US Classification:
514 24, 51421201, 514178, 514146, 514176, 514 50, 514 25, 5142634, 514 44 R, 514171, 514170, 514 75, 514 93, 514 48
Abstract:
The present invention provides a compound which is an inhibitor of sphingolipid biosynthesis for use in the treatment of a disease which has a secondary Niemann-Pick type C disease like cellular phenotype.