Inventors:
Charles J. Dimitroff - Hanover MA, US
Filiberto Cedeno Laurent - Jamaica Plain MA, US
Steven R. Barthel - Allston MA, US
Assignee:
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. - Boston MA
International Classification:
A61K 39/395, C12N 15/13, C12N 15/63, A61P 35/00, C12N 5/10, C12N 1/19, C12P 21/00, A61P 37/06, C07K 19/00, C12N 1/21
US Classification:
4241341, 5303873, 536 234, 4353201, 43525233, 435348, 4352542, 435325, 435 696
Abstract:
Described are Galectin-1/Ig fusion constructs and methods of use thereof, e.g., in diagnostic and biomedical assays, and as therapeutic agents for the treatment of conditions associated with immune dysfunction, e.g., autoimmune diseases, and cancers.