Inventors:
Dave S.B. Hoon - Los Angeles CA, US
Farin Amersi - Los Angeles CA, US
Assignee:
John Wayne Cancer Institute - Santa Monica CA
International Classification:
A61K 39/395, C12Q 1/02, C12Q 1/68, G01N 33/53, A61P 31/00, A61K 38/00, A61K 31/7088
US Classification:
4241411, 435 29, 435 6, 435 71, 514 12, 514 44, 4241721
Abstract:
The invention relates to methods for determining whether a melanoma will metastasize or has metastasized to the small intestine in a subject by detecting or quantifying the expression of the CCR9, CCL25/TECK, or integrin α4 gene. Also disclosed are methods for treating subjects so identified.