Inventors:
Evan Beckman - Newton MA, US
Graham K. Farrington - Acton MA, US
Werner Meier - Burlington MA, US
Jeffrey L. Browning - Brookline MA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
A61K 38/00, A61K 38/16, A61K 45/00, C12P 21/06, C12P 21/04, C12N 15/00, C12N 5/00, C07H 21/04, C07K 1/00, C07K 14/00
US Classification:
514 166, 514 212, 4242781, 435 691, 435 697, 435 703, 4353201, 435325, 536 234, 536 235, 530350, 530402
Abstract:
This invention relates to methods of treating disease with soluble inhibitors of the lymphotoxin pathway having improved properties. This invention also relates to improved LTBR-Ig fusion proteins, and pharmaceutical compositions thereof.