Inventors:
A. MacLeod - Montreal, CA
Gregory Reid - Pointe-Claire, CA
Jeffrey Besterman - Bai D' Urfe, CA
Ernest Borden - Pepper Pike OH, US
Frederic Reu - Shaker Heights OH, US
International Classification:
A61K 48/00, A61K 31/7072, A61K 31/53, A61K 31/513
US Classification:
514044000, 514049000, 514242000, 514269000
Abstract:
The invention provides methods for the treatment of cancer comprising a reduction of DNA methyltransferase expression and/or activity and treatment and/or induction of interferon. The invention overcomes resistance of cancer cells to interferon