Inventors:
Jeffrey Dean Isaacson - Superior CO, US
Mical Raponi - San Francisco CA, US
James Ranger-Moore - Tucson AZ, US
Eric L. Powell - Oceanside CA, US
Assignee:
VENTANA MEDICAL SYSTEMS, INC. - Tucson AZ
CLOVIS ONCOLOGY, INC. - Boulder CO
International Classification:
A61K 31/7068, C07H 19/00
Abstract:
The subject invention relates to determining the presence and level of hENT1 expression in tumor tissue that is appropriate for gemcitabine therapy, and more importantly, the level of hENT1 expression that signifies that treatment with a gemcitabine derivative is a more appropriate strategy.