ERIC P SANDGREN
Veterinary in Philadelphia, PA
License number
Pennsylvania BV006045L
Category
Veterinary Medicine
Type
Veterinarian
Address
Address
Philadelphia, PA 19107
Professional information
Method Of Preparing Recombinant Proteins In Transgenic Animals Containing Metallothionein Gene Elements That Bestow Tissue-Independent Copy Number-Dependent, Position-Indepedent Gene Expression
US Patent:
5583009, Dec 10, 1996
Filed:
Dec 8, 1992
Appl. No.:
7/986963
Inventors:
Richard Palmiter - Seattle WA
Eric P. Sandgren - Philadelphia PA
Ralph L. Brinster - Gladwyne PA
Eric P. Sandgren - Philadelphia PA
Ralph L. Brinster - Gladwyne PA
Assignee:
University of Washington - Seattle WA
The Trustees of the University of Pennsylvania - Philadelphia PA
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
C12P 2102, C12P 2100, C12N 1509, C07H 2104
US Classification:
435691
Abstract:
Vertebrate gene locus control regions linked to a structural gene of interest and inserted into a transgenic animal are capable of bestowing tissue-independent, copy number-dependent, position-independent gene expression. Recombinant proteins of interest encoded by structural genes linked to the metallothionein locus control regions may be prepared following expression in transgenic animal hosts.