ERIC OTTO FEIGL
Medical Practice in Seattle, WA
License number
Pennsylvania MD008302E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Seattle, WA 98105
Pennsylvania
Pennsylvania
Personal information
See more information about ERIC OTTO FEIGL at radaris.comName
Address
Phone
2360 43Rd Ave E APT 311, Seattle, WA 98112
2360 43Rd St, Seattle, WA 98112
2360 43Rd Ave E, Seattle, WA 98112
Professional information
Professor At Washington University School Of Medicine
Location:
Greater Seattle Area
Industry:
Higher Education
Dr. Eric O Feigl, Seattle WA - MD (Doctor of Medicine)
Specialties:
Cardiology
Address:
1705 NE Pacific St, Seattle 98195
357290 Health Sci SUITE G424, Seattle 98195
(206) 543-1496 (Phone), (206) 685-0619 (Fax)
357290 Health Sci SUITE G424, Seattle 98195
(206) 543-1496 (Phone), (206) 685-0619 (Fax)
Languages:
English
Education:
Medical School
University of Mn Med Sch
Graduated: 1958
University of Mn Med Sch
Graduated: 1958
Eric O Feigl, Seattle WA
Specialties:
Family Physician
Address:
Physiology 357290 Health Sci, Seattle, WA 98195
Real-Time In-Vivo Measurement Of Myoglobin Oxygen Saturation
US Patent:
5931779, Aug 3, 1999
Filed:
Jun 6, 1997
Appl. No.:
8/870483
Inventors:
Lorilee S. Arakaki - Narberth PA
Eric Feigl - Seattle WA
Martin J. Kushmerick - Seattle WA
David Marble - Seattle WA
David H. Burns - Montreal, CA
Kenneth H. Schenkman - Madison WI
Eric Feigl - Seattle WA
Martin J. Kushmerick - Seattle WA
David Marble - Seattle WA
David H. Burns - Montreal, CA
Kenneth H. Schenkman - Madison WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61B 500
US Classification:
600310
Abstract:
A method for determining myoglobin oxygen fractional saturation in vivo in muscle tissue and intracellular oxygen tension (pO. sub. 2), typically in the presence of hemoglobin, is provided. The method comprises measuring the absorption spectrum of the tissue using spectrographic equipment known to the art, including equipment for non-invasively taking spectroscopic measurements of tissue, or adaptations of such equipment to provide the preferred measurements described herein, or using spectrographic equipment specifically designed as described herein for use in non-invasive measurements of reflectance spectra. The measured spectrum is corrected for light scattering effects, such as by taking the second derivative of the data, or by using other means which are known to the art. Myoglobin fractional oxygen saturation is calculated from the measured spectrum employing calibration coefficients that are themselves calculated from application of multivariate analysis to a calibration set created from the second derivatives of absorption spectra. The calibration set spectra preferably representing absorbances of (1) a range of concentrations of hemoglobin (wherein a range of concentrations of oxyhemoglobin and deoxyhemoglobin are present), (2) one concentration of myoglobin (preferably selected to match the concentration of myoglobin in the target muscle tissue) with varying relative amounts of oxy- and deoxymyoglobin and (3) a range of concentrations of scattering agents to mimic scattering encountered in target tissue.
Optical Measurement Of Cellular Energetics
US Patent:
2008020, Aug 21, 2008
Filed:
Nov 29, 2007
Appl. No.:
11/947242
Inventors:
Kenneth A. Schenkman - Seattle WA, US
Lorilee S.L. Arakaki - Bainbridge Island WA, US
Wayne A. Ciesielski - Seattle WA, US
Eric O. Feigl - Seattle WA, US
David H. Burns - Point Claire, CA
Lorilee S.L. Arakaki - Bainbridge Island WA, US
Wayne A. Ciesielski - Seattle WA, US
Eric O. Feigl - Seattle WA, US
David H. Burns - Point Claire, CA
International Classification:
A61B 5/00
US Classification:
600310
Abstract:
This document discloses, among other things, systems and methods for measuring a level of myoglobin, hemoglobin, and cytochrome using an optical probe coupled to a spectrometer. Multivariate analysis of the spectral data yields quantifiable cellular and mitochondrial characteristics.