Inventors:
Eric A. Johnson - Madison WI
Huei-hsiung Yang - Rockville MD
Beril Geldiay-Tuncer - Bostanli-Karsiyaka, TR
William T. Hall - Rockville MD
David Schreiber - Columbia MD
Kwok Ho - San Diego CA
Assignee:
Igene Biotechnology, Inc. - Columbia MD
International Classification:
C12N 116, C12P 2300
Abstract:
An economical process for in vivo production of the pigment astaxanthin, and particularly a process for enhancing astaxanthin content of cultures of microorganisms of genus Phaffia, the process comprising culturing a microorganism of genus Phaffia in a nutrient medium containing an antibiotic, a cytochrome B inhibitor, or a terpenoid synthetic pathway inhibitor, cultivating surviving pigment enhanced microorganisms, and harvesting the yeast.