Inventors:
Eric L. Nelson - Santa Ana CA
Assignee:
Nelson Research & Development Company - Irvine CA
International Classification:
A61K 3514, A61K 31685, A61K 3166
Abstract:
A process for inhibiting platelet aggregation or thrombus formation by the addition of a member selected from the group consisting of a compound of the formula: ##STR1## WHEREIN X is an alkyl or alkenyl chain having 2-8 carbon atoms, one of which carbon atoms may be in the form of a carbonyl group, Y is H, alkyl, dialkylaminoethyl, aryl, aralkyl or aryl and aralkyl substituted with one or more R, and R is H, lower alkyl, lower alkoxy, halogen, CF. sub. 3, NO. sub. 2, OH, CN, COOR. sub. 1, ##STR2## NHCOR. sub. 1, NR. sub. 1 R. sub. 2 or ##STR3## where R. sub. 1 and R. sub. 2 are each selected from the group consisting of H and lower alkyl; R, R. sub. 1 and R. sub. 2 being the same or different and n is 0-5; and pharmaceutically acceptable salts thereof, to in vivo and in vitro platelet systems.