DR. EMMANUEL JEAN-MARIE MIGNOT, M.D., PH.D.
Neurology at Quarry Rd, Palo Alto, CA
License number
California A67085
Category
Psychiatric
Type
Sleep Medicine
License number
California A67085
Category
Neurology
Type
Neurology
Address
Address
401 Quarry Rd STE 3301, Palo Alto, CA 94304
Phone
(650) 725-6512
(650) 724-5299 (Fax)
(650) 724-5299 (Fax)
Professional information
Dr. Emmanuel J Mignot, Palo Alto CA - MD (Doctor of Medicine)
Specialties:
Neurology
Address:
Palo Alto Office
401 Quarry Rd, Palo Alto 94304
(650) 723-6643 (Phone)
Stanford Sleep Disorders Clinic
450 Broadway St, Redwood City 94063
(650) 723-6601 (Phone)
401 Quarry Rd, Palo Alto 94304
(650) 723-6643 (Phone)
Stanford Sleep Disorders Clinic
450 Broadway St, Redwood City 94063
(650) 723-6601 (Phone)
Languages:
English
Hospitals:
Palo Alto Office
401 Quarry Rd, Palo Alto 94304
Stanford Sleep Disorders Clinic
450 Broadway St, Redwood City 94063
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
401 Quarry Rd, Palo Alto 94304
Stanford Sleep Disorders Clinic
450 Broadway St, Redwood City 94063
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Education:
Medical School
Universite De Paris, Faculte De Medecine
Graduated: 1985
Universite De Paris, Faculte De Medecine
Graduated: 1985
Treatment Of Cns Disorders Using Cns Target Modulators
US Patent:
2005008, Apr 14, 2005
Filed:
Apr 23, 2004
Appl. No.:
10/831553
Inventors:
Dale Edgar - Wayland MA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Boston MA, US
Emmanuel Mignot - Palo Alto CA, US
James White - Carlisle MA, US
Michael Solomon - Concord MA, US
Kazumi Shiosaki - Wellesley MA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Boston MA, US
Emmanuel Mignot - Palo Alto CA, US
James White - Carlisle MA, US
Michael Solomon - Concord MA, US
Kazumi Shiosaki - Wellesley MA, US
International Classification:
C07D413/02, C07D043/02
US Classification:
546022000, 546268100, 546269100, 514089000, 514340000
Abstract:
The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention is directed to the compositions and use of derivatized, histamine antagonists for the treatment of sleep disorders.
Treatment Of Cns Disorders Using Cns Target Modulators
US Patent:
2003018, Oct 2, 2003
Filed:
Oct 16, 2002
Appl. No.:
10/272510
Inventors:
Dale Edgar - Wayland MA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
Assignee:
Hypnion, Inc. - Worcester MA
International Classification:
A61K031/4545, A61K031/4439, C 07D 4 5/02, C 07D 4 3/02, A61K031/44, A61K031/445
US Classification:
514/317000, 514/343000, 514/320000, 546/196000, 546/216000, 546/237000, 546/276400
Abstract:
The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
Cns Target Modulators
US Patent:
2004014, Jul 22, 2004
Filed:
Dec 4, 2003
Appl. No.:
10/728340
Inventors:
Dale Edgar - Wayland MA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
Assignee:
Hypnion, Inc. - Worcester MA
International Classification:
C 07D 4 9/02, C 07D 4 5/02, A61K031/445
US Classification:
514/320000, 514/325000, 546/196000, 546/203000
Abstract:
The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
Treatment Of Cns Disorders Using Cns Target Modulators
US Patent:
2005000, Jan 13, 2005
Filed:
Oct 16, 2002
Appl. No.:
10/492990
Inventors:
Dale Edgar - Wayland MA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
David Hangauer - East Amherst NY, US
Harry Leighton - Brookline MA, US
Emmanuel Mignot - Palo Alto CA, US
International Classification:
A61K038/00, A61K031/519, A61K031/445, A61K031/5513
US Classification:
514002000, 514220000, 514221000, 514259410, 514317000
Abstract:
The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
Emmanuel Jean-Marie Mignot, Palo Alto CA
Specialties:
Neurology, Psychiatry, Surgical Oncology, Sleep Medicine
Work:
Center For Narcolepsy
701 Welch Rd, Palo Alto, CA 94304 Stanford Sleep Medicine Ctr MC5704
450 Broadway St, Redwood City, CA 94063
701 Welch Rd, Palo Alto, CA 94304 Stanford Sleep Medicine Ctr MC5704
450 Broadway St, Redwood City, CA 94063
Education:
Universite De Paris (1985)
Emmanuel Jean-Marie Mignot, Palo Alto CA
Specialties:
Psychiatrist
Address:
401 Quarry Rd, Palo Alto, CA 94304
450 Broadway St, Redwood City, CA 94063
450 Broadway St, Redwood City, CA 94063
Hypocretin Receptor In Regulation Of Sleep And Treatment Of Sleep Disorders
US Patent:
2005004, Mar 3, 2005
Filed:
Jun 14, 2004
Appl. No.:
10/868379
Inventors:
Emmanuel Mignot - Palo Alto CA, US
Juliette Faraco - Menlo Park CA, US
Hua Li - Union City CA, US
Ling Lin - Mountain View CA, US
Seiji Nishino - Palo Alto CA, US
Hiroshi Kadatoni - Hiroshima, JP
Juliette Faraco - Menlo Park CA, US
Hua Li - Union City CA, US
Ling Lin - Mountain View CA, US
Seiji Nishino - Palo Alto CA, US
Hiroshi Kadatoni - Hiroshima, JP
International Classification:
C12Q001/68
US Classification:
435006000
Abstract:
The present invention is directed to methods for identification of compounds that affect wakefulness, attention deficit hyperactivity disorder, chronic fatigue syndrome and mood disorders (e.g., depression) through interaction with the hypocretin receptor system. The present invention is also directed to detection of abnormal levels of hypocretin in a subject, as well as detection of an abnormal immune response against hypocretin (orexins) and/or their receptors, where detection of abnormal hypocretin levels or detection of an abnormal immune response is indicative of a sleep disorder, particularly of narcolepsy. The present invention is also directed to a methods relating to the detection of a mutation or polymorphism in the gene encoding the hypocretin receptors, the detection of antibodies disrupting the function of gene encoding hypocretin receptors and hypocretin polypeptides, and the use of hypocretin biological markers in predicting treatment response using compounds interacting with the hypocretin receptor system.