ELIZABETH TRANQUIL
Medical Practice at Cpe Pointe Cir, Jupiter, FL

2012002, Feb 2, 2012

Oct 6, 2010

12/899464

Dennis Tranquil - Jupiter FL, US
Albert Vladimirovich Kanarsky - Volzhsk, RU
Elizabeth Tranquil - Jupiter FL, US
Zosya Albertovna Kanarskaya - Kazan, RU
Oleg Nickolaevich Okunev - Puschino, RU

CUBENA, INC. - Jupiter FL

A61K 36/06

424115, 42419516

A method of rendering harmless mycotoxins contaminating food, animal feed and assisting infection of plant hosts by microbial parasites is proposed. The method comprises binding mycotoxins by a novel adsorbent, consisting partially or in full of the biomass of filamentous fungi or isolated fungal biomass components, such as chitin, chitozan and hyrdophobins, or fungal biomass enriched in its capacity to bind said mycotoxins using fungal species and strain selection, genetic engineering of fungi, modification of fungal fermentation conditions and downstream physical and chemical treatment of fungal biomass, such as milling or micronization in a dry state. The resulting adsorbent can bind a wide range of mycotoxins, including the ones difficult to bind (Ochratoxin, T-2, DON, NIV) using a current generation of mycotoxin adsorbents based on clay, resins, yeast and bacterial biomass. The adsorbent can be used as an animal feed additive, functional food additive and agricultural fungistatic/fungicide.

2012007, Mar 22, 2012

Sep 15, 2011

13/233021

Dennis Tranquil - Jupiter FL, US
Albert Vladimirovich Kanarsky - Volzhsk, RU
Elizabeth Tranquil - Jupiter FL, US
Zosya Albertovna Kanarskaya - Kazan, RU
Arthur Tigranovich Kopylov - Engels, RU

Cubena, Inc. - Jupiter FL

A01N 65/34, A01N 65/44, A01P 1/00, A01N 65/06, A01N 65/00, A01N 65/12, A01N 65/08

424735, 424764, 424750, 424725, 424770, 514 22

Method is proposed useful to render harmless mycotoxins that contaminate food, animal feed and assist infection of plant hosts by microbial parasites, comprising binding mycotoxins by a novel adsorbent, consisting partially or in full of plant lignocellulosic biomass or isolated biomass components, e.g., acid hydrolysis lignin, enzymatic hydrolysis lignin, coniferous and deciduous wood, bark and needle particles, rice hulls, used coffee grounds, apricot stone shells, almond, walnut, sunflower hulls, cocoa and peanut shells. The materials may be further improved through genetic modification of plants and physicochemical treatment of lignocellulosic biomass, such as micronization. The resulting adsorbent can bind wide range of mycotoxins, including, mycotoxins difficult to bind (Ochratoxin, T-2, Deoxynivalenol, Nivalenol). Ability of porous materials containing lignin to thermally collapse at melting can be used to irreversibly entrap mycotoxins by adsorbing them in a wet system and then closing lignin pore structure under high-temperature treatment, such as drying.

2012008, Apr 5, 2012

Sep 29, 2011

13/248522

Dennis Theodore Tranquil - Jupiter FL, US
Elizabeth Tranquil - Jupiter FL, US

CUBENA, INC. - Jupiter FL

A23L 1/30, A23L 1/305, A23K 1/16, A23L 1/302

426 62

A method for upgrading human food and animal feed, rendering harmless the contaminating mycotoxins, increasing protein and nucleotide content, providing immuno-modulation, enhancing flavor and palatability is proposed. The method comprises a food functional additive/supplement and feed additive based on yeast biomass processed to enhance the bioavailability and biological activity of its components using dry micron milling with optional agglomeration. The resulting product contains all biologically active components originally present in intact live yeast. Compared to existing practice, the new process is much faster, cheaper, less hardware demanding, less prone to microbial contamination, provides intact biopolymers and results in insoluble product fraction with high surface area. Human food and animal feed containing such additive improves weight gains, feed efficiency, resilience to mycotoxin contamination, improves immunological status, controls intestinal and other bacteria and decreases mortality, especially at the young age, replacing antibiotics and growth promoters.

8496984, Jul 30, 2013

Dec 28, 2009

12/648139

Elizabeth Tranquil - Jupiter FL, US
Zosya Albertovna Kanarskaya - Kazan, RU
Dmitry Fedorovich Tikhomirov - Moscow, RU
Albert Vladimirovich Kanarsky - Voljzsk, RU

Cubena, Inc. - Jupiter FL

A23B 7/154, B01J 20/00

426321, 502404

Mycotoxins prevailing in Northern climates have been until now proven difficult to deactivate in animal feed by binding, in contrast to mycotoxins prevailing in the Southern climates. Meanwhile, both types of toxins present a considerable risk factor for agricultural animal health and performance. A method of adsorbing and rendering harmless for animals an expanded range of both Northern and Southern mycotoxins found in contaminated feed is proposed. According to the invention, a combination of modified plant ligno-polysaccharide material and traditional mycotoxin binding components is added to the feed of agricultural and companion animals in an amount sufficient to abate the negative effects of both types of mycotoxins present.