ELIZABETH J. WATERS, M.D.
Medical Practice at Euclid Ave, San Diego, CA

License number
California A113933
Category
Medical Practice
Type
Pediatrics
Address
Address
292 Euclid Ave SUITE 220, San Diego, CA 92114
Phone
(619) 262-8624
(619) 262-6639 (Fax)
National Provider ID: 1730477621
LicenseFiles verified this license of Nov 7, 2017 at the National Plan and Provider Enumeration System.

Professional information

Elizabeth Waters Photo 1

Associate Professor Of Biology At San Diego State University
Position:
Associate Professor of Biology at San Diego State University
Location:
Greater San Diego Area
Industry:
Research
Work:
San Diego State University since 2008 - Associate Professor of Biology Diversa Corporation Jun 2000 - Aug 2002 - Scientist Bioinformatics Diversa 2000 - 2002 - Staff Scientist University of Arizona 1993 - 1996 - Post-Doc Washington University in St. Louis 1986 - 1993 - Graduate Student
Education:
Washington University in St. Louis 1986 - 1993
Ph.D., Evolutionary Biology Grinnell College 1979 - 1983
BA, Biology North Carolina State University
MS, Botany
Interests:
Molecular Evolution, Genome Evolution, Evolution of Protein Families

Elizabeth Waters Photo 2

Amidases, Nucleic Acids Encoding Them And Methods For Making And Using Them

US Patent:
2006025, Nov 16, 2006
Filed:
Jan 28, 2003
Appl. No.:
10/502832
Inventors:
Nelson Barton - SAN DIEGO CA, US
David Weiner - Del Mar CA, US
William Greenberg - San Diego CA, US
Samantha Luu - San Diego CA, US
Kristine Chang - San Diego CA, US
Elizabeth Waters - San Diego CA, US
International Classification:
A01K 67/027, A01H 5/00, C12N 1/21, C12Q 1/68, C07H 21/04, C07D 501/00, C12N 9/80, C07D 501/14, C12N 15/74, C12N 15/82, C12P 35/02
US Classification:
800018000, 536023200, 435006000, 435228000, 435252300, 435471000, 800288000, 540222000, 435051000
Abstract:
This invention provides amidases, polynucleotides encoding the amidases, methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides enzymes having secondary amidase activity, e.g., having activity in the hydrolysis of amides, including enzymes having peptidase, protease and/or hydantoinase activity. In alternative aspects, the enzymes of the invention can be used to used to increase flavor in food (e.g., enzyme ripened cheese), promote bacterial and fungal killing, modify and de-protect fine chemical intermediates, synthesize peptide bonds, carry out chiral resolutions, hydrolyze Cephalosporin C. The enzymes of the invention can be used to generate 7-aminocephalosporanic acid (7-ACA) and semi-synthetic cephalosporin antibiotics, including caphalothin, cephaloridine and cefuroxime. The enzymes of the invention can be used as antimicrobial agents, e.g., as cell wall hydrolytic agents. The invention also provides a fluorescent amidase substrate comprising 7-(ε-D-2-aminoadipoyladipoylamido)-4-methylcoumarin.

Elizabeth Waters Photo 3

Enzymes Having Secondary Amidases Activity And Methods Of Use Thereof

US Patent:
2004002, Feb 5, 2004
Filed:
Jan 28, 2003
Appl. No.:
10/354437
Inventors:
Nelson Barton - San Diego CA, US
David Weiner - Del Mar CA, US
William Greenberg - San Diego CA, US
Samantha Luu - San Diego CA, US
Kristine Chang - San Diego CA, US
Elizabeth Waters - San Diego CA, US
Assignee:
Diversa Corporation - San Diego CA
International Classification:
C12Q001/68, G06F019/00, G01N033/48, G01N033/50, C07H021/04, C12N009/80
US Classification:
435/006000, 435/069100, 435/228000, 435/320100, 435/325000, 536/023200, 702/019000
Abstract:
This invention provides amidases, polynucleotides encoding the amidases, methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides enzymes having secondary amidase activity, e.g., having activity in the hydrolysis of amides, including enzymes having peptidase, protease and/or hydantoinase activity. In alternative aspects, the enzymes of the invention can be used to used to increase flavor in food (e.g., enzyme ripened cheese), promote bacterial and fungal killing, modify and de-protect fine chemical intermediates, synthesize peptide bonds, carry out chiral resolutions, hydrolyze Cephalosporin C. The enzymes of the invention can be used to generate 7-aminocephalosporanic acid (7-ACA) and semi-synthetic cephalosporin antibiotics, including caphalothin, cephaloridine and cefuroxime. The enzymes of the invention can be used as antimicrobial agents, e.g., as cell wall hydrolytic agents. The invention also provides a fluorescent amidase substrate comprising 7-( -D-2-aminoadipoylamido)-4-methylcoumarin.

Elizabeth Waters Photo 4

Glucosidases, Nucleic Acids Encoding Them And Methods For Making And Using Them

US Patent:
2007005, Mar 8, 2007
Filed:
Mar 18, 2004
Appl. No.:
10/550155
Inventors:
Kevin Gray - San Diego CA, US
James Garrett - San Diego CA, US
Nahla Aboushadi - Katy TX, US
Ryan Knowles - Chula Vista CA, US
Eileen O'Donoghue - San Diego CA, US
Elizabeth Waters - San Diego CA, US
Assignee:
DIVERSA CORPORATION - San Diego CA
International Classification:
A01K 67/027, C12Q 1/68, C07H 21/04, C12P 21/06, C12N 9/42, A01H 1/00, C12N 5/04
US Classification:
800018000, 435069100, 435209000, 435320100, 435325000, 536023200, 435006000, 800284000, 435419000
Abstract:
The invention is directed to polypeptides having a glucosidase activity, including an alpha-glucosidase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention are used as alpha-glucosidases to catalyze the hydrolysis of starch into sugars, e.g., to convert liquefied starch to glucose. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both alpha-(1,4) and alpha-(1,6) glucose linkages. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both malto-oligosaccharides and liquefied starch.

Elizabeth Waters Photo 5

Nanoarchaeum Genome, Nanoarchaeum Polypeptides And Nucleic Acids Encoding Them And Methods For Making And Using Them

US Patent:
2008016, Jul 10, 2008
Filed:
May 1, 2003
Appl. No.:
10/428340
Inventors:
Karl O. Stetter - Regensubrg, DE
Elizabeth Waters - San Diego CA, US
Keith Kretz - San Marcos CA, US
Mircea Podar - San Diego CA, US
Toby Richardson - San Diego CA, US
Michiel Noordewier - San Diego CA, US
Assignee:
Diversa Corporation - San Diego CA
International Classification:
A01K 67/00, C07H 21/04, C07K 16/00, C12N 15/00, C12N 1/34, C12Q 1/68, C40B 50/06, G01N 33/48, G06G 7/48, C40B 40/10, G01N 33/53, C12N 5/06, C12N 5/00, A01H 5/00
US Classification:
800 8, 536 232, 536 243, 536 2433, 530350, 4353201, 435325, 800298, 536 245, 435375, 435183, 5303873, 506 18, 435 71, 435 6, 703 11, 702 19, 536 2541, 506 26, 800288, 4352521
Abstract:
The invention provides a genome of the hyperthermophile , polypeptides, including enzymes, structural protein and binding proteins, derived from this genome, polynucleotides encoding these polypeptides, methods of making and using these polynucleotides and polypeptides. The invention also provides isolated hyperthermophile

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