DR. ELIZABETH ANNE TRACHTENBERG, PH.D.
Medical Practice in Oakland, CA
License number
California DRK24
Category
Medical Practice
Type
Medical Genetics, Ph.D. Medical Genetics
Address
Address
2
747 Blmrb STE 204, Oakland, CA 94609
2960 Benvenue Ave, Berkeley, CA 94705
2960 Benvenue Ave, Berkeley, CA 94705
Phone
(510) 450-7685
(510) 450-5692 (Fax)
(510) 665-4747
(510) 450-5692 (Fax)
(510) 665-4747
Personal information
See more information about ELIZABETH ANNE TRACHTENBERG at radaris.comName
Address
Phone
2960 Benvenue Ave, Berkeley, CA 94705
2527 Ridge Rd, Berkeley, CA 94709
Professional information
Dr. Elizabeth A Trachtenberg, Oakland CA - PHD
Specialties:
Medical Genetics
Address:
747 52Nd St SUITE 204, Oakland 94609
(510) 450-7685 (Phone), (510) 450-5692 (Fax)
(510) 450-7685 (Phone), (510) 450-5692 (Fax)
Languages:
English
Oligonucleotide Primers For Hla Class I B Locus Dna Typing
US Patent:
5550039, Aug 27, 1996
Filed:
Mar 7, 1995
Appl. No.:
8/399675
Inventors:
Elizabeth A. Trachtenberg - Berkeley CA
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12P 1934, C07H 2104
US Classification:
435 912
Abstract:
The present invention provides primers for the polymerase chain reaction amplification of a nucleic acid sequence encompassing the polymorphic regions of the second, third, and fourth exons of the HLA Class I B gene (HLA-B). The polymorphic regions of the second, third, and fourth exons of the HLA-B gene contain sufficient variability so that each allele is uniquely identified by the nucleic acid sequence within these regions. The primers and amplification methods of the present invention enable genotyping at the HLA-B locus using samples from a variety of sources and for detecting allelic variants not distinguishable by serological methods. The HLA-B DNA genotyping can be used for tissue typing, determining individual identity, and identifying disease susceptible individuals.
Determination Of Kir Haplotypes Associated With Disease
US Patent:
2011012, Jun 2, 2011
Filed:
Sep 17, 2010
Appl. No.:
12/884602
Inventors:
Martha Ladner - Oakland CA, US
Elizabeth Trachtenberg - Berkeley CA, US
Lloyd Gordon Bentley - Alameda CA, US
Damian Goodridge - Darlington, AU
Henry A. Erlich - Oakland CA, US
Elizabeth Trachtenberg - Berkeley CA, US
Lloyd Gordon Bentley - Alameda CA, US
Damian Goodridge - Darlington, AU
Henry A. Erlich - Oakland CA, US
Assignee:
ROCHE MOLECULAR SYSTEMS, INC. - Pleasanton CA
International Classification:
C12Q 1/68, C07H 21/04
US Classification:
435 611, 536 2433
Abstract:
Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
Methods And Compositions For Kir Genotyping
US Patent:
7919279, Apr 5, 2011
Filed:
Sep 21, 2006
Appl. No.:
12/088229
Inventors:
Elizabeth A. Trachtenberg - Oakland CA, US
Kathleen Houtchens - Oakland CA, US
Robert J. Nichols - Oakland CA, US
Kathleen Houtchens - Oakland CA, US
Robert J. Nichols - Oakland CA, US
Assignee:
Children's Hospital & Research Center at Oakland - Oakland CA
International Classification:
C12P 19/34, C07H 21/04
US Classification:
435 912, 536 2433
Abstract:
The present invention provides methods for single nucleotide polymorphism (SNP)-based killer cell immunoglobulin-like receptor (KIR) gene cluster genotyping using the matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer. In general, the methods involve amplifying a plurality of target sequences of a plurality of KIR genes, and detecting the presence or absence of a plurality of single SNPs of the plurality of KIR genes by MALDI-TOF mass spectrometry. The invention also features compositions, including arrays of capture primers and optionally extension primers on a substrate surface, and kits, for use in the methods of the invention.