ELIO P MARIANI
Pharmacy in Lancaster, PA
License number
Pennsylvania RP042251R
Category
Pharmacy
Type
Pharmacist
Address
Address
Lancaster, PA 17601
Professional information
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Transdermal Delivery Of Active Drugs
Transdermal Delivery Of Active Drugs
US Patent:
5762952, Jun 9, 1998
Filed:
Apr 27, 1993
Appl. No.:
8/052768
Inventors:
Scott D. Barnhart - York PA
Elio P. Mariani - Lancaster PA
Elio P. Mariani - Lancaster PA
Assignee:
Hercon Laboratories Corporation - New York NY
International Classification:
A61F 1302
US Classification:
424448
Abstract:
A transdermal delivery system is described, including a backing layer having coated thereon an active drug-containing adhesive layer which includes (a) an acrylic-based adhesive which is self-crosslinking at a temperature of from about 20. degree. C. to about 65. degree. C. and (b) an active drug. A method for manufacturing a transdermal delivery system is also described, including (A) mixing an active drug with an acrylic-based adhesive solution which is self-crosslinking at a temperature of from about 20. degree. C. to about 65. degree. C. to form an active drug-adhesive mixture, (B) forming a coating of the active drug-adhesive mixture on a backing layer, and (C) drying the coating to form an active drug-containing adhesive layer. Examples of the active drug include nitroglycerin and estradiol.