Inventors:
Ru Chih C. Huang - Baltimore MD, US
Richard Park - Ithaca NY, US
Chih-Chuan Chang - Baltimore MD, US
Yu-Chuan Liang - Baltimore MD, US
David Mold - Baltimore MD, US
Elaine Lin - New York NY, US
Jonathan Heller - Raleigh NC, US
Neil Frazer - Cary NC, US
International Classification:
A61K 31/225, A61K 31/05, A61K 9/127, A61K 31/09, A61K 31/222, A61P 35/00, A61P 29/00, A61P 31/18
US Classification:
424450, 514734, 514721, 514547, 514551
Abstract:
The present invention provides kits, methods and compositions for the treatment of diseases such as cancers. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment by a route other than direct injection into the affected tissues or topical application on affected tissues.