Inventors:
Evan C. Unger - Tucson AZ
Thomas A. Fritz - Tucson AZ
Edward W. Gertz - Paradise Valley AZ
Assignee:
ImaRx Pharmaceutical Corp. - Tucson AZ
International Classification:
A61B 800, A61K 9127
Abstract:
Novel contrast agents which may be used for diagnostic and therapeutic use. The compositions may comprise a lipid, a protein, polymer and/or surfactant, and a gas, in combination with a targeting ligand. In preferred embodiments, the targeting ligand targets coagula, including emboli and/or thrombi, particularly in patients suffering from an arrhythmic disorder. The contrast media can be used in conjunction with diagnostic imaging, such as ultrasound, as well as therapeutic applications, such as therapeutic ultrasound.