DR. EDWARD VICTOR ROSS, MD
Dermatology in San Diego, CA

5810801, Sep 22, 1998

Feb 5, 1997

8/794876

R. Rox Anderson - Lexington MA
Edward Victor Ross - San Diego CA
James C. Hsia - Weston MA
Kathleen McMillan - Concord MA

Candela Corporation - Wayland MA
The United States of America as represented by the Secretary of the Navy - Washington DC

A61B 1736

606 9

A method for treating wrinkles in skin involves the use of a beam of puls scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1. 2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1. 3 and 1. 8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.

6120497, Sep 19, 2000

Sep 15, 1998

9/153052

R. Rox Anderson - Lexington MA
Edward Victor Ross - San Diego CA
James C. Hsia - Weston MA
Kathleen McMillan - Concord MA

Massachusetts General Hospital - Boston MA
Candela Corporation - Wayland MA
United States of America - Washington DC

A61B 1818

606 9

A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1. 2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1. 3 and 1. 8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.

2007019, Aug 23, 2007

Dec 22, 2006

11/645222

Yacov Domankevitz - Newton MA, US
Edward Ross - San Diego CA, US

A61B 18/18, A61N 5/06

606009000, 607089000

A beam of radiation can be provided to treat a dermatological condition in a target region of skin. The beam of radiation can have a wavelength between about 700 nm and about 800 nm, a fluence greater than about 50 J/cm, and a pulse duration between about 10 msec and about 300 msec. The beam of radiation is delivered to the target region of skin to affect (i) at least one pigmentary abnormality disposed in an epidermal region of the target region and (ii) at least one vascular abnormality disposed in a dermal region of the target region. A surface of the epidermal region of the target region of skin can be cooled to prevent substantial unwanted injury to at least a portion of the epidermal region.

2008026, Oct 30, 2008

Jul 3, 2008

12/167720

R. Rox Anderson - Lexington MA, US
Edward Victor Ross - San Diego CA, US
James C. Hsia - Weston MA, US
Kathleen McMillan - Concord MA, US

A61B 18/28

606 9

A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.

2004014, Jul 22, 2004

Oct 31, 2003

10/698970

R. Anderson - Lexington MA, US
Edward Ross - San Diego CA, US
James Hsia - Weston MA, US
Kathleen McMillan - Concord MA, US

A61B018/20, A61N005/06

606/009000, 607/088000, 607/089000

A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.

2005025, Nov 17, 2005

Jun 8, 2005

11/148051

R. Anderson - Lexingotn MA, US
Edward Ross - San Diego CA, US
James Hsia - Weston MA, US
Kathleen McMillan - Concord MA, US

A61B018/20

606009000, 607088000, 607089000

A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.