EDWARD RICHARD SAUTER
Medical Practice in Philadelphia, PA
License number
Pennsylvania MD043734L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Philadelphia, PA 19107
Personal information
See more information about EDWARD RICHARD SAUTER at radaris.comName
Address
Phone
5150 Dairy Rd, Red Lion, PA 17356
2766 Shangri La Rd, Stewartstown, PA 17363
3601 Spruce St, Philadelphia, PA 19104
3 Latham Park, Elkins Park, PA 19027
609 Meadowbrook Dr, Huntingdon Valley, PA 19006
Professional information
Nipple Aspirate Fluid Specific Microarrays
US Patent:
2001003, Nov 8, 2001
Filed:
Jan 19, 2001
Appl. No.:
09/765791
Inventors:
Edward Sauter - Philadelphia PA, US
International Classification:
C12M003/00, C12M001/34, C07H021/04, C07H021/02, C12Q001/68
US Classification:
435/006000, 536/023100, 435/287200, 435/288300
Abstract:
A method is provided for aid in the diagnosis of breast cancer. Nipple aspirate fluid (“NAF”) is collected from the breast via a modified breast pump device. Breast epithelial cells (“BECs”) and proteins present in NAF are isolated. Nucleic acid is extracted from the BECs. The nucleic acids and secreted proteins are analyzed via a low-density nucleic acid and peptidic biopolymeric array, respectively. The level of RNA transcription, protein expression, and heterozygosity is compared to that of normal control cells. This invention has particular application to the early detection of breast cancer and the study of individual responses to chemo- and radiotherapeutic exposures.