EDWARD JOSEPH KASARSKIS, MD
Neurology in Lexington, KY
License number
Kentucky 21091
Category
Neurology
Type
Neurology
Address
Address
740 S LIMESTONE, Lexington, KY 40536
Phone
(859) 323-5661
(859) 257-7910
(859) 257-7910
Personal information
See more information about EDWARD JOSEPH KASARSKIS at radaris.comName
Address
Phone
305 Glendover Rd, Lexington, KY 40503
Lexington, KY
305 Glendover Rd, Lexington, KY 40503
Professional information
Dr. Edward J Kasarskis, Lexington KY - MD (Doctor of Medicine)
Specialties:
Neuropsychiatry (Neurology)
Address:
UK Neurology Sciences Institute
Dept Of Neurology Kentucky, Lexington 40536
(859) 323-5661 (Phone)
Dept Of Neurology Kentucky, Lexington 40536
(859) 323-5661 (Phone)
Certifications:
Neurology, 1981
Awards:
Healthgrades Honor Roll
Languages:
English, Spanish
Education:
Medical School
University Of Wisconsin Medical School
Graduated: 1974
University Of Wisconsin Madison
Graduated: 1975
University Of Virginia
Graduated: 1979
Graduated: 1976
University Of Wisconsin Medical School
Graduated: 1974
University Of Wisconsin Madison
Graduated: 1975
University Of Virginia
Graduated: 1979
Graduated: 1976
Edward Joseph Kasarskis, Lexington KY
Specialties:
Neurology
Work:
KY Clinic Dept of Neurology
740 S Limestone St, Lexington, KY 40536
740 S Limestone St, Lexington, KY 40536
Education:
University of Wisconsin at Madison (1974)
Diagnostic Test And Therapy For Manganese Superoxide Dismutate (Mnsod) Associated Diseases
US Patent:
6265172, Jul 24, 2001
Filed:
Feb 8, 2000
Appl. No.:
9/499884
Inventors:
Daret K. St. Clair - Lexington KY
Muneyasu Urano - Shiruoka, JP
Edward J. Kasarskis - Lexington KY
Muneyasu Urano - Shiruoka, JP
Edward J. Kasarskis - Lexington KY
Assignee:
University of Kentucky - Lexington KY
International Classification:
C12Q 168, C12P 1934, A61K 4800, C07H 2102
US Classification:
435 6
Abstract:
The present invention provides a diagnostic method and a kit for detection of mutations localized within the 5' promoter region of the MnSOD gene. Such mutations are associated with diseases characterized by decreased MnSOD activity such as certain formes of cancer, and ALS. Accordingly, the diagnostic method this invention provides, comprising RFLP, direct sequencing, or PCR analysis of the region within 3 kb, the transcription initiation site will detect these disorders. This invention also provides a therapeutic method for such disorders comprising transfection of affected cells or tissues with high activity, MnSOD expression vectors, or the administration of exogenous MnSOD enzyme.