EDWARD CHI-YEE MIAO
Pilots at 44 Ave, Seattle, WA
License number
Washington A3975212
Issued Date
Jul 2015
Expiration Date
Jul 2016
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
10009 44Th Ave NE, Seattle, WA 98125
Professional information
Flagellin Polypeptide Vaccines
US Patent:
2009029, Dec 3, 2009
Filed:
Apr 24, 2009
Appl. No.:
12/429971
Inventors:
Alan A. Aderem - Seattle WA, US
Edward A. Miao - Seattle WA, US
Carrie M. Rosenberger - Seattle WA, US
Edward A. Miao - Seattle WA, US
Carrie M. Rosenberger - Seattle WA, US
International Classification:
A61K 39/00, A61K 39/12, A61K 39/02
US Classification:
4241921, 4242051, 4242351
Abstract:
Vaccines that comprise or generate immunomodulatory flagellin polypeptides able to stimulate an innate immune response intracellularly and extracellularly employ viruses, bacteria or parasitic cells that contain expression systems for such polypeptides, as well as fusion proteins that contain antigens and/or cell penetrating peptides along with the immunomodulatory peptide.
Secretion-Related Bacterial Proteins For Nlrc4 Stimulation
US Patent:
2010032, Dec 23, 2010
Filed:
May 21, 2010
Appl. No.:
12/785300
Inventors:
Alan A. Aderem - Seattle WA, US
Edward A. Miao - Seattle WA, US
Edward A. Miao - Seattle WA, US
International Classification:
A61K 39/02, A61K 39/12, A61K 39/00, G01N 33/566, C12N 15/63, C07K 14/195, C12N 7/01, C12N 1/21, C12N 1/11, A61P 37/04, A61P 31/00
US Classification:
4241921, 4241991, 4242001, 4242341, 435 721, 4353201, 530350, 435236, 4352523, 4352581
Abstract:
Introduction of immunomodulatory T3SS polypeptides (IT3SSP's) into cells stimulates a response mediated by NLRC4 intracellularly. Introduction of said IT3SSP into the cells of a subject evoke an innate immune response in the subject.