Inventors:
Virginia M.Y. Lee - Philadelphia PA, US
Edward B. Lee - Philadelphia PA, US
John Q. Trojanowski - Philadelphia PA, US
International Classification:
A61K 39/395, C07K 16/00, C12N 5/07, A61P 25/28
US Classification:
4241331, 5303891, 435346, 5303881, 5303873, 4241721, 4241521
Abstract:
Provided is an antibody that selectively binds to an epitope formed by residues 1-11 of Aβ in an Aβ oligomer, a method comprising using the antibody to treat a disease characterized by such an Aβ amyloid deposit in a patient, and kits comprising same.