EDITH VIONI SULLIVAN
Psychologist in Palo Alto, CA
License number
Massachusetts 3124
Issued Date
Nov 19, 1982
Expiration Date
Jun 30, 2018
Type
Psychologist
Address
Address
Palo Alto, CA 94301
Professional information
Magnetic Resonance Spectroscopic Imaging Method To Monitor Progression And Treatment Of Neurodegenerative Conditions
US Patent:
6819952, Nov 16, 2004
Filed:
Mar 22, 2002
Appl. No.:
10/105028
Inventors:
Adolf Pfefferbaum - Los Altos Hills CA
Elfar Adalsteinsson - Palo Alto CA
Daniel Mark Spielman - Menlo Park CA
Edith V. Sullivan - Palo Alto CA
Elfar Adalsteinsson - Palo Alto CA
Daniel Mark Spielman - Menlo Park CA
Edith V. Sullivan - Palo Alto CA
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61B 505
US Classification:
600410, 600407, 600408, 600425, 382260, 382285, 382302, 382307
Abstract:
A non-invasive longitudinal method that is sensitive and objective for quantifying progressive loss of neurons in normal aging brains and brains that suffer from a neurodegenerative disease is provided. The method also provides clinicians, patients and drug companies with a method for evaluating the efficacy of various treatments and interventions by assessing a change in brain integrity. The method determines and localizes a change in brain integrity in a compartment of a brain from at least structural images and metabolite brain images, which are acquired for at least two time instances. The time period between two time instances is dependent on the disease pathology and disease progression and could, for instance, be at least 3 months between time instances as well as at least 6 or 12 months between time instances.