Inventors:
Stephen Allen - Milford MA
Hubert Koster - Hamburg, DE
Edward Ashare - Framingham MA
Donald W. Euwart - Natick MA
Jennifer Fernandes - Milford MA
Assignee:
Hybridon, Inc. - Cambridge MA
International Classification:
B23B 2700
Abstract:
An apparatus and process are disclosed for optimizing the repetitive steps in a solid-phase oligonucleotide synthesis by continuous optical scanning of the effluent stream from the reaction module and by computerized processing and implementation of the scanning data.