DONALD L SIEGEL, MD
Medical Practice at Spruce St, Philadelphia, PA
License number
Pennsylvania MD044574R
Category
Medical Practice
Type
Anatomic Pathology
License number
Pennsylvania MD044574E
Category
Medical Practice
Type
Clinical Pathology/Laboratory Medicine
Address
Address
3400 Spruce St, Philadelphia, PA 19104
Phone
(215) 662-6503
Personal information
See more information about DONALD L SIEGEL at radaris.comName
Address
Phone
2582 Brandon Ct, Lansdale, PA 19446
2582 Brandon Ct, Worcester, PA 19490
2582 Brandon Ct, Lansdale, PA 19446
103 Marble Dr, Canonsburg, PA 15317
261 Maple St, Rillton, PA 15678
Organization information
See more information about DONALD L SIEGEL at bizstanding.comDonald L Siegel MD
S 34 St At Walnut St, Philadelphia, PA 19104
Categories:
Physicians & Surgeons
Phone:
(215) 898-9655 (Phone)
Payment options:
All Major Cards Accepted, American Express, MasterCard, ...
Professional information
Donald Lawrence Siegel, Philadelphia PA
Specialties:
Pathology, Anatomic Pathology, Clinical Pathology/Laboratory Medicine
Work:
Hospital of the University of PA
3400 Spruce St, Philadelphia, PA 19175
3400 Spruce St, Philadelphia, PA 19175
Education:
University of Pennsylvania(1987)
Dr. Donald L Siegel, Philadelphia PA - MD (Doctor of Medicine)
Specialties:
Clinical Pathology
Address:
Philadelphia Office
3400 Spruce St, Philadelphia 19104
(800) 789-7366 (Phone), (215) 662-4613 (Fax)
3400 Spruce St, Philadelphia 19104
(800) 789-7366 (Phone), (215) 662-4613 (Fax)
Certifications:
Clinical Pathology, 1992
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Philadelphia Office
3400 Spruce St, Philadelphia 19104
Hospital of the University of Pennsylvania
3400 Spruce St, Philadelphia 19104
3400 Spruce St, Philadelphia 19104
Hospital of the University of Pennsylvania
3400 Spruce St, Philadelphia 19104
Education:
Medical School
Perelman School of Medicine University of Pennsylvania
Graduated: 1987
U Penn Hosp
Perelman School of Medicine University of Pennsylvania
Graduated: 1987
U Penn Hosp
Phage Particle Diagnostic Reagents
US Patent:
2010001, Jan 21, 2010
Filed:
Nov 14, 2006
Appl. No.:
12/085618
Inventors:
Donald Siegel - Philadelphia PA, US
Assignee:
THE TRUSTEE OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
THE SCRIPPS RESEARCH INSTITUTE - La Jolla CA
THE SCRIPPS RESEARCH INSTITUTE - La Jolla CA
International Classification:
C12Q 1/70
US Classification:
435 5
Abstract:
The present invention relates to novel methods for detecting a member of a known binding pair in a sample, including a cell, where one member of the pair (termed the “receptor”) is expressed by a bacteriophage, which phage is then used to detect the presence of the other member of the pair (termed the “ligand” or “target”). Rather than detecting the binding of the phage using antibody-based technology, the present invention relates to detecting marker molecule associated with the phage. In one aspect, the invention relates to identifying an antigen-bearing moiety (e.g., a red blood cell antigen) of interest present on a cell, e.g., a red blood cell, using antibody-displaying bacteriophage, as well as detecting anti-red blood cell auto- or alloantibodies and/or complement in a sample, using antiglobulin reagent-displaying bacteriophage and detecting a marker molecule associated with the phage. In one aspect, the phenotype of the phage is not linked with the genotype of the phage.