Inventors:
Donald Rubin - Nashville TN, US
Edward Organ - Nashville TN, US
Raymond Dubois - Franklin TN, US
International Classification:
C12Q001/70, C12Q001/68, C07H021/04, C12P021/06, C12N015/09, C07K014/82
US Classification:
435005000, 435006000, 435069100, 435320100, 435325000, 530350000, 536023200
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.