DR. DONALD HOWARD RUBIN, M.D.
Osteopathic Medicine in Nashville, TN

License number
Tennessee 0000022165
Category
Osteopathic Medicine
Type
Infectious Disease
Address
Address
3601 Tvc, Nashville, TN 37232
Phone
(615) 322-3000

Professional information

Donald H Rubin Photo 1

Dr. Donald H Rubin, Nashville TN - MD (Doctor of Medicine)

Specialties:
Infectious Disease Medicine
Address:
1310 24Th Ave S STE F201, Nashville 37212
(615) 327-5346 (Phone), (615) 321-6305 (Fax)
3601 Tvc, Nashville 37232
(615) 322-3000 (Phone)
Certifications:
Infectious Disease, 1978, Internal Medicine, 1977
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1310 24Th Ave S STE F201, Nashville 37212
3601 Tvc, Nashville 37232
Vanderbilt University Hospital
1211 Medical Center Dr, Nashville 37232
Education:
Medical School
Weill Cornell Medical College
Mount Sinai Hospital
Brigham and Womens Hospital


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
6777177, Aug 17, 2004
Filed:
Mar 31, 2000
Appl. No.:
09/509712
Inventors:
Donald H. Rubin - Nashville TN
Edward L. Organ - Nashville TN
Raymond N. Dubois - Franklin TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
C12Q 170
US Classification:
435 5, 435 6, 435 72, 435 32, 435325
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
6448000, Sep 10, 2002
Filed:
Mar 8, 1999
Appl. No.:
09/171209
Inventors:
Donald H. Rubin - Nashville TN
Edward L. Organ - Nashville TN
Raymond N. Dubois - Franklin TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
C12Q 168
US Classification:
435 6, 435440, 435325, 4352523, 536 231, 536 235
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
2005024, Nov 3, 2005
Filed:
Jan 12, 2005
Appl. No.:
11/033764
Inventors:
Donald Rubin - Nashville TN, US
Edward Organ - Nashville TN, US
Raymond Dubois - Franklin TN, US
International Classification:
C12Q001/70, C12Q001/68, C07H021/04, C12P021/06, C12N015/09, C07K014/82
US Classification:
435005000, 435006000, 435069100, 435320100, 435325000, 530350000, 536023200
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
2003002, Feb 6, 2003
Filed:
Aug 27, 2002
Appl. No.:
10/228794
Inventors:
Donald Rubin - Nashville TN, US
Edward Organ - Nashville TN, US
Raymond Dubois - Franklin TN, US
International Classification:
C12Q001/68, C07H021/04, C12N009/00, C12P021/02, C12N005/06
US Classification:
435/006000, 435/069100, 435/183000, 435/320100, 435/325000, 530/350000, 536/023200
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.


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Adam10 And Its Uses Related To Infection

US Patent:
8247451, Aug 21, 2012
Filed:
Jan 16, 2007
Appl. No.:
12/160862
Inventors:
Donald H. Rubin - Nashville TN, US
Thomas Hodge - Athens GA, US
James Murray - Bogart GA, US
Assignee:
Vanderbilt University - Nashville TN
University of Georgia Research Foundation - Athens GA
The United States of America as represented by the Department of Veterans Affairs - Washington DC
International Classification:
A61K 31/19, A61K 31/18, A61K 31/155
US Classification:
514575, 514601, 514602, 514634
Abstract:
The present invention relates to a protein, ADAM10, ADAM10 nucleic acid sequences and ADAM10 proteins encoded by these sequences that are involved in infection by one or more pathogen such as a virus, a parasite, a bacteria or a fungus or are otherwise associated with the life cycle of a pathogen.


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Mammalian Genes Involved In Tularemia And Other Infections

US Patent:
2013006, Mar 14, 2013
Filed:
Jun 14, 2010
Appl. No.:
13/377815
Inventors:
Donald Rubin - Nashville TN, US
Robert Gilmore - Fort Collins CO, US
Thomas Hodge - Athens GA, US
Natalie McDonald - Atlanta GA, US
International Classification:
A61K 31/713, A01K 67/027, C12N 5/071
US Classification:
800 14, 435375, 514 44 A
Abstract:
The present invention relates to nucleic acid sequences and cellular proteins encoded by these sequences that are involved in infection or are otherwise associated with the life cycle of one or more pathogens.


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
2009009, Apr 9, 2009
Filed:
Sep 15, 2008
Appl. No.:
12/210869
Inventors:
Donald H. Rubin - Nashville TN, US
Edward L. Organ - Nashville TN, US
Raymond N. Dubois - Franklin TN, US
International Classification:
A61K 39/395, C07H 21/00, C12N 1/00, A61P 31/12, C12Q 1/70, C07K 14/00
US Classification:
4241301, 536 231, 435243, 530350, 435 5
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus-free cell cultures and methods for screening for additional such genes.


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Rab9A, Rab11A, And Modulators Thereof Related To Infectious Disease

US Patent:
2007008, Apr 19, 2007
Filed:
Feb 24, 2005
Appl. No.:
10/590844
Inventors:
Thomas Hodge - Roswell GA, US
Natalie McDonald - Atlanta GA, US
Donald Rubin - Nashville TN, US
Michaewl Shaw - Decatur GA, US
Anthony Sanchez - Lilbum GA, US
James Murray - Lawrenceville GA, US
International Classification:
A01K 67/00, G01N 33/53, A61K 48/00, A61K 39/40
US Classification:
424163100, 800013000, 435007100, 514044000
Abstract:
Disclosed herein are methods of reducing infection of a cell by a pathogen, for example to treat or prevent a pathogen infection. Exemplary pathogens include those that use a lipid raft. The disclosure also relates to methods of identifying agents involved in pathogen infection, such as modulators of Rab9A and Rab11A.


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Mammalian Genes Involved In Viral Infection And Tumor Suppression

US Patent:
2005011, May 26, 2005
Filed:
Jun 25, 2004
Appl. No.:
10/877807
Inventors:
Donald Rubin - Nashville TN, US
Edward Organ - Nashville TN, US
Raymond Dubois - Franklin TN, US
International Classification:
C12Q001/70, C07H021/04, C12P021/02, C07K014/52
US Classification:
435005000, 435069500, 435320100, 435325000, 530351000, 536023500
Abstract:
The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus- free cell cultures and methods for screening for additional such genes.