DONALD BRUCE BORDERS
Pilots at Heather Hl Ln, Airmont, NY

6737403, May 18, 2004

Jul 13, 2001

09/904352

Donald B Borders - Suffern NY
William V Curran - Pearl River NY
Amedeo A Fantini - New City NY
Noreen D Francis - Harriman NY
Howard Jarolmen - Fair Lawn NJ
Richard A Leese - Suffern NY

Micrologix Biotech Inc. - Vancouver

A61K 3812

514 11, 530317

The present invention provides laspartomycin core peptides, laspartomycin core peptide derivatives, antimicrobial laspartomycin derivatives, methods for making laspartomycin core peptides, methods for making laspartomycin core peptide derivatives, methods for making antimicrobial laspartomycin derivatives, pharmaceutical compositions of antimicrobial laspartomycin derivatives, methods of inhibiting microbial growth and methods for treating and/or preventing microbial infections in a subject.

6716962, Apr 6, 2004

Sep 6, 2001

09/948374

Donald B Borders - Suffern NY
Noreen D Francis - Harriman NY
Amedeo A Fantini - New City NY

Micrologix Biotech Inc. - Vancouver

C07K 114

530317, 435 713, 530323, 530344

The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics, such as those having a cyclic peptide or cyclic depsipeptide core, in high yield and purity. In particular, there is provided a method of extracting a variety of acidic lipopeptide antibiotics, directly or indirectly, into water immiscible organic solvents by using a divalent cation chelation procedure.

4608343, Aug 26, 1986

May 30, 1985

6/739334

David P. Labeda - Monsey NY
Joseph J. Goodman - Spring Valley NY
Donald B. Borders - Suffern NY
Raymond T. Testa - Cedar Grove NJ
John H. E. J. Martin - late of New City NY

American Cyanamid Company - Stamford CT

C12P 2100, C12P 1300, C12P 106

435253

This disclosure describes four new antibacterial agents designated LL-C08078. alpha. sub. 1, LL-C08078. alpha. sub. 2, LL-C08078. alpha. sub. 3 and LL-C08078. beta. produced in a microbiological fermentation under controlled conditions using a new strain of a new species of the genus Streptomyces called Streptomyces majorciensis Labeda, sp. nov. , and mutants thereof. These new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found. In addition, these agents are active as growth promotants in warm-blooded animals.

RE29903, Feb 6, 1979

Feb 22, 1977

5/770481

Jane P. Kirby - New City NY
Donald B. Borders - Suffern NY

American Cyanamid Company - Stamford CT

C07H 1512, C07H 1504

536 17

This disclosure describes a novel class of antibiotics, three of which have been designed AM31. alpha. , AM31. beta. , and AM31. gamma. and are produced in a microbiological fermentation under controlled conditions using a new strain of Streptoverticillium netropsis.

4774184, Sep 27, 1988

Aug 14, 1985

6/765418

Taikwang M. Lee - Holmdel NJ
Donald B. Borders - Suffern NY
Joseph J. Goodman - Spring Valley NY
Raymond T. Testa - Cedar Grove NJ
William M. Maiese - Bridgewater NJ
David P. Labeda - Peoria IL

American Cyanamid Company - Stamford CT

C12P 1716, C12N 120, C12R 103

435118

The invention is a process for the production by fermentation of the antibacterial and antiparasitic agents designated LL-D42067. alpha. , to methods for its recovery and concentration from crude solutions and to processes for its purification. The invention includes within its scope the biologically pure culture of the antibiotic.

4650765, Mar 17, 1987

Jul 30, 1985

6/760870

Jane P. Kirby - New City NY
Amedeo A. Fantini - New City NY
Donald B. Borders - Suffern NY
Raymond T. Testa - Cedar Grove NJ
John H. E. J. Martin - late of New City NY

American Cyanamid Company - Stamford CT

C12P 1912, C12P 2102

435254

This invention relates to two new antibacterial and anti-tumor agents designated LL-BO1208. alpha. and LL-BO1208. beta. produced during microbiological fermentation, under controlled conditions, using the novel microorganism Streptoverticillium stramineum and mutants thereof.

5077277, Dec 31, 1991

Sep 5, 1989

7/403232

Douglas W. Phillipson - Princeton NJ
Guy T. Carter - Suffern NY
Donald B. Borders - Suffern NY

American Cyanamid Company - Wayne NJ

A61K 3170, C07H 700

514 25

Derivatives of antibiotics derived from the microorganism Streptomyces lydicus subspecies tanzanius, referred to as antibiotics LL-E19020 alpha and beta, are produced by chemical reaction. The derivatives are also active antibiotics useful in the treatment of bacterial infections.

4870019, Sep 26, 1989

Nov 21, 1986

6/933651

Jane P. Kirby - New City NY
Donald B. Borders - Suffern NY
May D. Lee - Monsey NY
William M. Maiese - Bridgewater NJ
Raymond T. Testa - Cedar Grove NJ
David P. Labeda - Peoria IL

American Cyanamid Company - Stamford CT

C12N 120, C12R 101

4352521

A new antibacterial agent designated LL-C19004 is described, which antibacterial agent is produced through microbiological fermentation, under controlled conditions using a new species of Saccharothrix, Saccharothrix espanaensis (NRRL 15764).

4578468, Mar 25, 1986

Mar 26, 1984

6/593159

Guy T. Carter - Suffern NY
Donald B. Borders - Suffern NY
Joseph J. Goodman - Spring Valley NY
David P. Labeda - Peoria IL

American Cyanamid Company - Stamford CT

C07D49812

546 35

Antibiotic LL-D42067. beta. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.

4859598, Aug 22, 1989

Jan 21, 1986

6/820048

Guy T. Carter - Suffern NY
Donald B. Borders - Suffern NY
Joseph J. Goodman - Spring Valley NY
David P. Labeda - Peoria IL

American Cyanamid Company - Stamford CT

C12R 104, C12P 1718, C12P 106

4352521

Antibiotic LL-D42067. beta. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.