DIANE M SIMEONE, MD
Radiology in Ann Arbor, MI
License number
Michigan 4301053273
Category
Radiology
Type
Surgery
Address
Address
1500 Floor Taubman Ctr, Ann Arbor, MI 48109
Phone
(734) 936-5738
(734) 936-2047
(734) 936-2047
Personal information
See more information about DIANE M SIMEONE at radaris.comName
Address
Phone
4838 Hidden Brook Ln, Ann Arbor, MI 48105
4838 Hidden Brook Ln, Scio Township, MI 48105
3533 Windemere Ct, Ann Arbor, MI 48105
Professional information
Dr. Diane M Simeone, Ann Arbor MI - MD (Doctor of Medicine)
Specialties:
General Surgery
Address:
University Michigan Medical Center
1500 E Medical Center Dr, Ann Arbor 48109
(734) 936-4179 (Phone)
1500 E Medical Center Dr, Ann Arbor 48109
(734) 936-4179 (Phone)
Procedures:
Adrenalectomy, Dressing and/or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy), Enterostomy (Laparoscopic or Open), Excision of Tumor of Stomach, Gallbladder Removal, Laparoscopic, Hepatectomy, Incisional/Ventral Hernia Repair, Open, Intestinal Transplant (incl. Enterectomy), Laparotomy, Lymph Node Biopsy or Excision, Pancreatectomy (incl. Pancreas Transplant & Whipple Procedure), Renal Transplant and Nephrectomy, Splenectomy, Splenectomy and Splenorrhaphy, Trigger Point Injections
Conditions:
Biliary Atresia, Carcinoma in Situ, Cholecystitis and Gallstones, Gallbladder & Biliary Tract Cancer, Hyperparathyroidism, Incisional Hernia, Intestinal Obstruction, Liver Cancer, Lung Cancer, Neuroendocrine Tumors, Pancreatic Cancer, Peripheral Arterial Aneurysm and Dissection, Secondary Malignancies, Stomach and Small Intestine Cancer, Ventral Hernia
Certifications:
General Surgery, 1996
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
University Michigan Medical Center
1500 E Medical Center Dr, Ann Arbor 48109
University of Michigan Health System
1500 East Medical Center Dr SPC 5474, Ann Arbor 48109
1500 E Medical Center Dr, Ann Arbor 48109
University of Michigan Health System
1500 East Medical Center Dr SPC 5474, Ann Arbor 48109
Education:
Medical School
Duke University School Of Medicine
Graduated: 1988
University Of Michigan
Graduated: 1995
Duke University School Of Medicine
Graduated: 1988
University Of Michigan
Graduated: 1995
Compositions And Methods For Treating And Diagnosing Pancreatic Cancer
US Patent:
8501472, Aug 6, 2013
Filed:
Feb 3, 2012
Appl. No.:
13/365371
Inventors:
Diane M. Simeone - Ann Arbor MI, US
Michael F. Clarke - Palo Alto CA, US
Michael F. Clarke - Palo Alto CA, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12N 5/071
US Classification:
435366
Abstract:
The present invention relates to the field of oncology and provides novel compositions and methods for diagnosing and treating pancreatic cancer. In particular, the present invention provides pancreatic cancer stem cells useful for the study, diagnosis, and treatment of solid tumors.
Expression Profile Of Pancreatic Cancer
US Patent:
2005000, Jan 13, 2005
Filed:
May 18, 2004
Appl. No.:
10/848259
Inventors:
Craig Logsdon - Houston TX, US
Samir Hanash - Ann Arbor MI, US
Diane Simeone - Ann Arbor MI, US
Samir Hanash - Ann Arbor MI, US
Diane Simeone - Ann Arbor MI, US
International Classification:
C12Q001/68, G01N033/53, G01N033/567
US Classification:
435006000, 435007200
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with pancreatic cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of pancreatic cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
Compositions And Methods For Diagnosing And Treating Pancreatic Cancer
US Patent:
2011009, Apr 21, 2011
Filed:
Mar 5, 2009
Appl. No.:
12/920755
Inventors:
Diane M. Simeone - Ann Arbor MI, US
Chenwei LI - Windsor, CA
Chenwei LI - Windsor, CA
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K 31/70, G01N 33/574, C12N 5/00, A61K 31/505, A61K 31/4545, A61K 31/403, A61P 35/00
US Classification:
514 49, 435 723, 435325, 514274, 514318, 514414
Abstract:
The present invention provides compositions and methods for treating and diagnosing the presence of solid tumor stem cells in a patient (e.g., based on the presence of c-Met). In certain embodiments, the presence or absence of solid tumor stem cells (e.g., pancreatic solid tumor stem cells) can be determined through the use of a single cells surface marker (e.g., c-Met). The present invention also provides methods for screening candidate compounds (e.g., c-Met antagonists) for the ability to inhibit the tumorigenisis of pancreatic solid tumor stem cells.
Diane Marie Simeone, Ann Arbor MI
Specialties:
Surgery
Work:
University of Michigan Medical School
1500 E Medical Center Dr, Ann Arbor, MI 48109
1500 E Medical Center Dr, Ann Arbor, MI 48109
Education:
Duke University(1988)
Pancreatic Cancer Markers
US Patent:
2011023, Sep 29, 2011
Filed:
Sep 9, 2009
Appl. No.:
13/060802
Inventors:
David M. Lubman - Ann Arbor MI, US
Diane M. Simeone - Ann Arbor MI, US
Chen Li - Ann Arbor MI, US
Diane M. Simeone - Ann Arbor MI, US
Chen Li - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - ANN ARBOR MI
International Classification:
G01N 33/574
US Classification:
436501
Abstract:
The present invention relates to pancreatic cancer markers. In particular, the present invention provides methods and compositions for the identification of protein glycosylation patterns associated with pancreatic cancer.
Methods For Diagnosing The Malignant Potential Of Pancreatic Cystic Lesions
US Patent:
2013000, Jan 3, 2013
Filed:
Dec 30, 2010
Appl. No.:
13/519766
Inventors:
Brian B. Haab - Jenison MI, US
Diane Simeone - Ann Arbor MI, US
Diane Simeone - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
Van Andel Research Institute - Grand Rapids MI
Van Andel Research Institute - Grand Rapids MI
International Classification:
G01N 33/574, C40B 30/04, A61B 5/153, C40B 40/10
US Classification:
506 9, 506 18, 435 79, 600578
Abstract:
A method of diagnosing the malignant potential of a pancreatic cystic lesion in a subject including: detecting a glycan alteration in MUC5AC in a sample of pancreatic cystic lesion fluid from a subject, determining whether the glycan alteration is differentially present in the sample, and diagnosing the malignant potential of the pancreatic cystic lesion. A method of diagnosing the malignant potential of a pancreatic cystic lesion in a subject including: (a) detecting a glycan alteration in MUC5AC in a sample of pancreatic cystic lesion fluid from a subject, (b) detecting CA 19-9 in the sample, (c) determining whether the glycan alteration and CA 19-9 are differentially present in the sample, and (d) diagnosing the malignant potential of the pancreatic cystic lesion. Related methods of treatment and kits also are included.
Multimodal Spectroscopic Systems And Methods For Classifying Biological Tissue
US Patent:
8239139, Aug 7, 2012
Filed:
Jun 5, 2009
Appl. No.:
12/479600
Inventors:
Mary-Ann Mycek - Ann Arbor MI, US
Malavika Chandra - Lansdale PA, US
James Scheiman - Sup Township MI, US
Robert H. Wilson - Ann Arbor MI, US
Diane Simeone - Ann Arbor MI, US
Barbara McKenna - Ann Arbor MI, US
Julianne Purdy - Ann Arbor MI, US
Malavika Chandra - Lansdale PA, US
James Scheiman - Sup Township MI, US
Robert H. Wilson - Ann Arbor MI, US
Diane Simeone - Ann Arbor MI, US
Barbara McKenna - Ann Arbor MI, US
Julianne Purdy - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
G01N 33/48, G06F 7/60, G06G 7/58
US Classification:
702 19, 702 20, 703 2, 703 11
Abstract:
Multimodal optical spectroscopy systems and methods produce a spectroscopic event to obtain spectroscopic response data from biological tissue and compare the response data with preset criteria configured to correlate the measured response data and the most probable attributes of the tissue, thus facilitating classification of the tissue based on those attributes for subsequent biopsy or remedial measures as necessary.
Methods And Compositions For The Identification Of Cancer Markers
US Patent:
2009013, May 28, 2009
Filed:
Mar 26, 2007
Appl. No.:
12/294316
Inventors:
David M. Lubman - Ann Arbor MI, US
Diane M. Simeone - Ann Arbor MI, US
Jia Zhao - Ann Arbor MI, US
Diane M. Simeone - Ann Arbor MI, US
Jia Zhao - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12Q 1/68, B01J 19/00, C07K 1/00, B01D 59/44, G01N 33/543, C12Q 1/00
US Classification:
435 6, 422 70, 530413, 436518, 435 4, 250282
Abstract:
The present invention relates to methods and compositions for the identification of cancer markers. In particular, the present invention provides methods and compositions for the identification of glycosylated proteins and protein glycosylation patterns. The present invention further provides cancer markers identified using the described methods.
Compositions And Methods For Treating Cancer
US Patent:
2009019, Jul 30, 2009
Filed:
Dec 12, 2008
Appl. No.:
12/333559
Inventors:
Diane Simeone - Ann Arbor MI, US
Mats Ljungman - Ann Arbor MI, US
Liang Xu - Ann Arbor MI, US
Lidong Wang - Ann Arbor MI, US
Mats Ljungman - Ann Arbor MI, US
Liang Xu - Ann Arbor MI, US
Lidong Wang - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K 31/7105, A61P 35/00, C12N 5/00, A61K 31/7068
US Classification:
514 44, 435377, 514 49
Abstract:
The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target ATDC (TRIM29) expression in cancer with ATDC overexpression.