Inventors:
Mark A. Atkinson - Gainesville FL, US
Gregory Simon - Gainesville FL, US
Clive Henry Wasserfall - Gainesville FL, US
Abraham Scaria - Cambridge MA, US
Desmond A. Schatz - Gainesville FL, US
Donna Armentano - Cambridge MA, US
Srinivas Shankara - Cambridge MA, US
International Classification:
A61K 39/395, A61P 3/10
Abstract:
In accordance with the subject invention, anti-thymocyte globulin (ATG) can be used to modulate a patient's immune response in order to prevent and/or delay the onset or the progression of type 1 diabetes. ATG treatment augments CD4+CD25+ cell frequencies and their functional activities.