Inventors:
Robert Huebner - Stroudsburg PA, US
Lorne Erdile - Stroudsburg PA, US
Donald Warakomski - Tannersville PA, US
Robert Becker - Henryville PA, US
Maryann Gray - Bartonsville PA, US
Derek Pyle - East Stroudsburg PA, US
International Classification:
C12Q001/68, C07H021/04, C12N015/09, A61K039/02, C07K014/195, C12N001/21
US Classification:
536023700, 424190100, 435006000, 435069300, 435252300, 435320100, 530359000
Abstract:
Heterologous lipidated proteins formed recombinantly are disclosed and claimed. The expression system can be The heterologous lipidated protein has a leader sequence which does not naturally occur with the protein portion of the lipidated protein. The lipidated protein can have the OspA leader sequence. The protein portion can be OspC, PspA, UreA, Ure B, or a fragment thereof. Methods and compositions for forming and employing the proteins are also disclosed and claimed.