Dennis Eshima
Pharmacy at Cottonwood Ln, Phoenix, AZ
License number
Colorado 10636
Issued Date
Oct 4, 1977
Renew Date
Nov 1, 2015
Expiration Date
Oct 31, 2017
Type
Pharmacist
Address
Address
3219 E Cottonwood Ln, Phoenix, AZ 85048
Professional information
Chief Scientific Officer, Director Of Operations At Biotech Cyclotron
Position:
Chief Scientific Officer, Director of Operations at Biotech Cyclotron
Location:
Phoenix, Arizona Area
Industry:
Medical Devices
Work:
Biotech Cyclotron
-
Chief Scientific Officer, Director of Operations
Syncor International/Cardinal Health
Sep 1999 - Sep 2003
-
Director of Operations
Resoultion Pharmaceuticals
Sep 1992 - Sep 1996
-
Director of Research and Development
Education:
University of Utah School of Medicine 1981 - 1985
PhD, Pharmaceutics
PhD, Pharmaceutics
Methods And Compositions For Drying In The Preparation Of Radiopharmaceuticals
US Patent:
2013002, Jan 24, 2013
Filed:
Jul 16, 2012
Appl. No.:
13/550188
Inventors:
Dennis B. ESHIMA - Phoenix AZ, US
Mehmet Husnu - Phoenix AZ, US
Henry Padgett - Hermosa Beach CA, US
Thomas A. Klausing - Powell OH, US
Chad E. Bouton - Powell OH, US
Herman Benecke - Columbus OH, US
Daniel B. Garbark - Blacklick OH, US
Mehmet Husnu - Phoenix AZ, US
Henry Padgett - Hermosa Beach CA, US
Thomas A. Klausing - Powell OH, US
Chad E. Bouton - Powell OH, US
Herman Benecke - Columbus OH, US
Daniel B. Garbark - Blacklick OH, US
International Classification:
C01B 7/00, C09K 3/00
US Classification:
423249, 252184
Abstract:
A method of drying a radioisotope solution having radioisotopes includes passing the radioisotope solution through a solid phase extraction column containing an anion exchange group, thereby trapping the radioisotopes in the column. The method also includes passing an eluent through the column, thereby removing the radioisotopes from the column. The eluent includes a cation trapping agent/salt complex, less than 4% water, and the remainder is a solvent. A method of producing the eluent includes reacting a cation trapping agent with a salt in the presence of less than 4% water and a solvent to form solubilized cation trapping agent/salt complex, wherein one of the cation trapping agent and the salt is present in en excess of a stoichiometric amount and ending the reaction when a predetermined amount of solubilized cation trapping agent/salt complex has been formed.
Systems, Methods And Devices For Producing, Manufacturing And Control Of Radiopharmaceuticals-Full
US Patent:
2013010, Apr 25, 2013
Filed:
Jul 16, 2012
Appl. No.:
13/550425
Inventors:
Dennis ESHIMA - Phoenix AZ, US
Mehmet Husnu - Phoenix AZ, US
Jim Stone - Alpharetta GA, US
Derrick Alcaide - Los Angeles CA, US
Henry Padgett - Dublin OH, US
Joseph E. Zambanini - Delaware OH, US
Thomas A. Klausing - Powell OH, US
Chad E. Bouton - Powell OH, US
Brian C. Kelley - Pataskala OH, US
Scott N. Danhof - Plain City OH, US
David A. Holley - Lancaster OH, US
Jeffrey T. Stroup - Upper Arlington OH, US
James B. Gleeson - Columbus OH, US
Eric Hassenpflug - Westerville OH, US
James A. Prescott - Columbus OH, US
Herman Benecke - Columbus OH, US
Daniel B. Garbark - Blacklick OH, US
Mehmet Husnu - Phoenix AZ, US
Jim Stone - Alpharetta GA, US
Derrick Alcaide - Los Angeles CA, US
Henry Padgett - Dublin OH, US
Joseph E. Zambanini - Delaware OH, US
Thomas A. Klausing - Powell OH, US
Chad E. Bouton - Powell OH, US
Brian C. Kelley - Pataskala OH, US
Scott N. Danhof - Plain City OH, US
David A. Holley - Lancaster OH, US
Jeffrey T. Stroup - Upper Arlington OH, US
James B. Gleeson - Columbus OH, US
Eric Hassenpflug - Westerville OH, US
James A. Prescott - Columbus OH, US
Herman Benecke - Columbus OH, US
Daniel B. Garbark - Blacklick OH, US
Assignee:
CARDINAL HEALTH 414, LLC - Dublin OH
International Classification:
B01J 19/00, B65B 1/00
US Classification:
536 282, 536122, 5483275, 422159, 422119, 422110, 53473
Abstract:
Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control.
Closed Vial Fill System For Aseptic Dispensing
US Patent:
2012022, Sep 6, 2012
Filed:
Dec 28, 2011
Appl. No.:
13/339226
Inventors:
Mehmet HUSNU - Phoenix AZ, US
Dennis Eshima - Phoenix AZ, US
Derrick Alcaide - Los Angeles CA, US
Scott N. Danhof - Plain City OH, US
Jim Gleeson - Columbus OH, US
Eric Hassenpflug - Westerville OH, US
Jim Prescott - Columbus OH, US
Dennis Eshima - Phoenix AZ, US
Derrick Alcaide - Los Angeles CA, US
Scott N. Danhof - Plain City OH, US
Jim Gleeson - Columbus OH, US
Eric Hassenpflug - Westerville OH, US
Jim Prescott - Columbus OH, US
Assignee:
CARDINAL HEALTH 414, LLC - Dublin OH
International Classification:
B65B 1/04, B65D 71/06
US Classification:
141 69, 206223, 141369
Abstract:
A closed path vial fill system includes a bulk product vial, a peristaltic pump operated by a stepper motor, a dispensing manifold assembly to which may be coupled at least one final product vial, an optional quality check station, and an optional waste collection system. A concentration, activity, and volume (CAV) sensor may be incorporated into the system to receive a radiopharmaceutical product directly from a synthesizing unit. A control system may be integrated into the system to provide automated control of various aspects of the radiopharmaceutical dispensing process. The system is used to aseptically dispense finished radiopharmaceuticals into receiving vessels, such as a Quality Control vial, a sterility vial, and/or final product vials, while providing users an efficient means for removing and discarding contaminated disposable components.
Method And System For Automated Quality Control Platform
US Patent:
2013001, Jan 17, 2013
Filed:
Jul 16, 2012
Appl. No.:
13/550030
Inventors:
Dennis Eshima - Phoenix AZ, US
Mehmet Husnu - Phoenix AZ, US
Jim Stone - Alpharetta GA, US
Mehmet Husnu - Phoenix AZ, US
Jim Stone - Alpharetta GA, US
Assignee:
CARDINAL HEALTH 414, LLC - Dublin OH
International Classification:
G06F 19/00
US Classification:
702 83
Abstract:
A method and system for performing automated quality control analysis of a plurality of radiopharmaceuticals are provided. The method includes uniquely identifying each of the plurality of radiopharmaceuticals, and identifying and implementing a tailored quality control program for each of the radiopharmaceuticals. The method further includes automatically performing a plurality of selected quality control tests for each of the radiopharmaceuticals based on the tailored quality control program, and collecting information produced by the plurality of selected quality control tests.
Methods For Synthesizing Labeled Compounds
US Patent:
2013006, Mar 7, 2013
Filed:
Jul 16, 2012
Appl. No.:
13/550055
Inventors:
Dennis ESHIMA - Phoenix AZ, US
Mehmet HUSNU - Phoenix AZ, US
Jim STONE - Alpharetta GA, US
Brian C. KELLEY - Pataskala OH, US
Mehmet HUSNU - Phoenix AZ, US
Jim STONE - Alpharetta GA, US
Brian C. KELLEY - Pataskala OH, US
Assignee:
CARDINAL HEALTH 414, LLC - Dublin OH
International Classification:
C07H 1/00
US Classification:
536122
Abstract:
The invention relates to methods for synthesizing compounds on solid supports. The invention also relates to synthesizing labeled compounds, such as those used in the field of radiopharmaceuticals. The invention relates to methods for synthesizing halogenated radiopharmaceuticals such as fludeoxyglucose (also known as fluorodeoxyglucose or FDG).
Czt Sensor For Tumor Detection And Treatment
US Patent:
2013006, Mar 7, 2013
Filed:
Sep 7, 2012
Appl. No.:
13/606591
Inventors:
Dennis ESHIMA - Phoenix AZ, US
Mehmet HUSNU - Phoenix AZ, US
Jim STONE - Alpharetta GA, US
Mehmet HUSNU - Phoenix AZ, US
Jim STONE - Alpharetta GA, US
Assignee:
CARDINAL HEALTH 414, LLC - Dublin OH
International Classification:
G01T 1/24, A61B 6/04, A61N 5/10, G01T 1/167
US Classification:
600431, 2503361, 250394, 25037013, 600 1
Abstract:
A tumor treatment apparatus may include an array of collimated CZT detectors configured to intersect a known coordinate and measure gamma radiation activity, for example at 511 keV. A radiation delivery system may be configured to direct radiation through the known coordinate on the basis of the gamma radiation activity. A translatable and rotatable table may be configured to support a tumor host, wherein the tumor is positionable relative to the known coordinate on the basis of the gamma radiation activity emitted by the tumor and measured by the array of collimated CZT detectors. Radiation from the radiation delivery system may be delivered to the tumor at the known coordinate, and may be delivered in an intra-operative surgical environment.