Inventors:
Delbert Linn Harris - Ames IA, US
Matthew Erdman - Ankeny IA, US
Kurt Iver Kamrud - Apex NC, US
Jonathan Smith - Cary NC, US
John Dustin Loy - Ames IA, US
Lyric Colleen Bartholomay - Ames IA, US
Ed Scura - Potomac MD, US
Assignee:
HARRISVACCINES, INC. - Ames IA
International Classification:
A61K 39/145, A61K 39/135, C12Q 1/04, C12N 7/00, C12Q 1/70, C07H 21/02, C07H 1/00, C12P 21/00, C12Q 1/68, C12P 19/34, A61K 39/12, C07H 21/04
US Classification:
4242101, 4242181, 4242041, 435 34, 4352351, 536 253, 435 691, 435 615, 435 912, 435 5
Abstract:
A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.