Inventors:
Elizabeth E. Evans - Bloomfield NY, US
Mark J. Paris - West Henrietta NY, US
Deepak M. Sahasrabudhe - Rochester NY, US
Maurice Zauderer - Pittsford NY, US
Ernest S. Smith - Ontario NY, US
Assignee:
VACCINEX, INC. - Rochester NY
International Classification:
A61K 39/395, C12N 5/00, C07K 16/00, C07H 21/00, C12N 15/63, C12P 21/00, G01N 33/53, A61P 35/00
US Classification:
4241391, 435375, 4241741, 5303871, 536 2353, 4353201, 435 696, 435325, 435 72
Abstract:
The present invention is directed to methods of killing cancer cells, the methods comprising administering at least one C35 antibody and a chemotherapeutic agent. In some preferred embodiments, two C35 antibodies are administered with a chemotherapeutic agent. The present invention is further directed to C35 antibodies useful in these methods.