Inventors:
Sylvia Daunert - Lexington KY, US
Sapna K. Deo - Fishers IN, US
Patrizia Pasini - Lexington KY, US
Anjali Kumari Struss - San Diego CA, US
Harohalli Shashidhar - Lexington KY, US
Deborah R. Auer Flomenhoft - Lexington KY, US
Nilesh Raut - Lexington KY, US
International Classification:
C12Q 1/68, C12Q 1/04, G01N 33/53
Abstract:
The presently-disclosed subject matter provides systems, methods, and kits for diagnosing and/or monitoring a bacteria-related condition of interest in a subject by providing a cell sensing system, each system containing a reporter molecule capable of detecting binding of a quorum sensing molecule and capable of generating a detectable signal.