DEBORAH KRAKOW, MD
Medical Practice at Le Conte Ave, Los Angeles, CA

License number
California G57061
Category
Medical Practice
Type
Orthopaedic Surgery
Address
Address
10833 Le Conte Ave, Los Angeles, CA 90095
Phone
(310) 319-1234

Organization information

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Deborah Krakow MD

8700 Beverly Blvd, Los Angeles, CA 90048

Industry:
Genetic Medicine, Orthopedics, Obgyn
Phone:
(800) 233-2771 (Phone)
Deborah Krakow

Professional information

Deborah Krakow Photo 1

Dr. Deborah Krakow, Los Angeles CA - MD (Doctor of Medicine)

Address:
Fetal Medical and Womens Ultrasound
6310 San Vicente Blvd STE 520, Los Angeles 90048
(323) 857-1952 (Phone)
Hospitals:
Fetal Medical and Womens Ultrasound
6310 San Vicente Blvd STE 520, Los Angeles 90048
Cedars - Sinai Medical Center
8700 West Beverly Blvd, West Hollywood 90048
Saint John's Health Center
2121 Santa Monica Blvd, Santa Monica 90404
Education:
Medical Schools
Rosalind Franklin University Of Medicine Science/The Chicago Medical School
Graduated: 1984


Deborah Krakow Photo 2

Professor At Ucla Medical Center

Position:
Professor at UCLA Medical Center
Location:
Greater Los Angeles Area
Industry:
Research
Work:
UCLA Medical Center since Jul 2008 - Professor
Education:
Arizona State University 1975 - 1979
B.S., History/Chemisty
Skills:
Clinical Research, Genetics, Molecular Biology, Genomics, Cell Biology, Medical Education


Deborah Krakow Photo 3

Deborah Krakow, West Hollywood CA

Specialties:
OB-GYN
Address:
8700 Beverly Blvd, West Hollywood, CA 90048
10833 Le Conte Ave, Los Angeles, CA 90095
Education:
Rosalind Franklin University, Chicago Medical School - Doctor of Medicine
Cedars-Sinai Medical Center - Residency - Obstetrics and Gynecology
Board certifications:
American Board of Medical Genetics Certification in Clinical Genetics (MD) (Medical Genetics), American Board of Obstetrics and Gynecology Certification in Obstetrics & Gynecology, American Board of Obstetrics and Gynecology Sub-certificate in Maternal and Fetal Medicine (Obstetrics & Gynecology)


Deborah Krakow Photo 4

Genetic Marker For Spondyloepimetaphyseal Dysplasia

US Patent:
2003019, Oct 16, 2003
Filed:
Jul 2, 2001
Appl. No.:
09/898200
Inventors:
Daniel Cohn - Santa Monica CA, US
Muhammad Faiyaz-Ul-Haque - Islamabad, PK
Lily King - Los Angeles CA, US
Deborah Krakow - Los Angeles CA, US
International Classification:
C12Q001/68, C07H021/04, A61K048/00, C12P019/34
US Classification:
514/044000, 435/006000, 435/091200, 536/023200, 536/024300
Abstract:
Disclosed are isolated polynucleotides containing nucleic acid segments encoding human or murine ATP sulfurylase/APS kinase, also known as PAPS synthetase (PAPSS), particularly PAPSS2 and Papss2 proteins. Also disclosed are nucleic acid constructs, including vectors, probes, primers, and primer pairs containing novel PAPSS2 and Papss2 gene sequences. A genetically modified vertebrate cell containing a nucleic acid construct of the present invention and a non-human vertebrate comprising the cell are also disclosed. Based on the present PAPSS2-specific polynucleotides and nucleic acid constructs, are genetic testing kits and methods for diagnosing spondyloepimetaphyseal dysplasia (SEMD) in a human subject, of identifying a human carrier of an heritable allele associated with SEMD, and of gene therapy or protein therapy for treating a human subject having an osteoarthritic disorder, which is caused or aggravated by deficient enzymatic sulfation activity. Also disclosed is a protein therapy method for treating a human subject having an osteoarthritic disorder caused or aggravated by deficient enzymatic sulfation activity that employs an inventive PAPSS2 fusion protein. Also disclosed are an isolated antibody or antibody fragment that selectively binds a PAPSS2 or Papss2 protein.


Deborah Krakow Photo 5

Deborah Krakow, West Hollywood CA

Specialties:
Obstetrics & Gynecology, Maternal & Fetal Medicine, Orthopaedic Surgery, Clinical Genetics, M.D.
Work:
Cedars-Sinai Medical Center
8700 Beverly Blvd, Los Angeles, CA 90048
Education:
Rosalind Franklin University (1984)


Deborah Krakow Photo 6

Associate Professor At Ucla Medical Center

Position:
Associate Professor at UCLA Medical Center
Location:
Greater Los Angeles Area
Industry:
Medical Practice
Work:
UCLA Medical Center - Associate Professor
Education:
Arizona State University 1975 - 1980


Deborah Krakow Photo 7

Associate Professor At Ucla

Position:
Associate Professor at UCLA
Location:
Greater Los Angeles Area
Industry:
Research
Work:
UCLA - Associate Professor


Deborah Krakow Photo 8

3-Phosphoadenosine-5-Phosphosulfate (Paps) Synthetase Proteins And Methods For Treating Osteoarthritic Disorders

US Patent:
6818428, Nov 16, 2004
Filed:
Jul 2, 2001
Appl. No.:
09/898165
Inventors:
Daniel H. Cohn - Santa Monica CA
Muhammad Faiyaz-Ul-Haque - Islamabad, PK
Lily King - Los Angeles CA
Deborah Krakow - Los Angeles CA
Assignee:
Cedars Sinai Medical Center - Los Angeles CA
International Classification:
C12N 912
US Classification:
435194, 4352523, 4353201, 536 232, 4241921
Abstract:
Disclosed are isolated polynucleotides containing nucleic acid segments encoding human or murine ATP sulfurylase/APS kinase, also known as PAPS synthetase (PAPSS), particularly PAPSS2 and Papss2 proteins. Also disclosed are nucleic acid constructs, including vectors, probes, primers, and primer pairs containing novel PAPSS2 and Papss2 gene sequences. A genetically modified vertebrate cell containing a nucleic acid construct of the present invention and a non-human vertebrate comprising the cell are also disclosed. Based on the present PAPSS2-specific polynucleotides and nucleic acid constructs, are genetic testing kits and methods for diagnosing spondyloepimetaphyseal dysplasia (SEMD) in a human subject, of identifying a human carrier of an heritable allele associated with SEMD, and of gene therapy or protein therapy for treating a human subject having an osteoarthritic disorder, which is caused or aggravated by deficient enzymatic sulfation activity. Also disclosed is a protein therapy method for treating a human subject having an osteoarthritic disorder caused or aggravated by deficient enzymatic sulfation activity that employs an inventive PAPSS2 fusion protein. Also disclosed are an isolated antibody or antibody fragment that selectively binds a PAPSS2 or Papss2 protein.