DAVID WILLIAM POWELL
Medical Practice in Delaware
License number
Pennsylvania MD072776L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Delaware
Wayne, PA 19087
Wayne, PA 19087
Professional information
Yfii Pseudouridine Synthase
US Patent:
6361965, Mar 26, 2002
Filed:
Nov 12, 1998
Appl. No.:
09/190824
Inventors:
David J. Powell - Radnor PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07H 2104
US Classification:
435 691, 536 232, 536 237, 536 231, 4353201, 435325, 435455
Abstract:
The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides enconding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibaterial compound.
Yfii Pseudouridine Synthase
US Patent:
6110723, Aug 29, 2000
Filed:
Nov 12, 1998
Appl. No.:
9/190821
Inventors:
David J. Powell - Radnor PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 990, C07H 2104
US Classification:
435233
Abstract:
The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides encoding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibacterial compounds.
Yfil Pseudouridine Synthase
US Patent:
6312932, Nov 6, 2001
Filed:
Mar 24, 2000
Appl. No.:
9/535493
Inventors:
David J. Powell - Radnor PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 900, C12N 990, A61K 3902
US Classification:
435183
Abstract:
The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides encoding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibacterial compounds.
Asp2
US Patent:
6319689, Nov 20, 2001
Filed:
Jan 20, 1998
Appl. No.:
9/009191
Inventors:
David J Powell - Radnor PA
Conrad G Chapman - Orpington, GB
Kay Murphy - Herts, GB
Trudi S Smith - Radnor PA
Conrad G Chapman - Orpington, GB
Kay Murphy - Herts, GB
Trudi S Smith - Radnor PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
SmithKline Beecham plc - Brentford
SmithKline Beecham plc - Brentford
International Classification:
C12P 2106, C12N 1509, C12N 120, C12N 1500, C07H 2102
US Classification:
435 691
Abstract:
ASP2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP2 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimer's Disease, cancer, and prohormone processing, among others, and diagnostic assays for such conditions.
Asp1
US Patent:
6025180, Feb 15, 2000
Filed:
Oct 6, 1997
Appl. No.:
8/999723
Inventors:
David J Powell - Radnor PA
Christopher Southan - Bishops Stortford, GB
Conrad G Chapman - Orpington, GB
Joanne R Evans - Bishops Stortford, GB
Christopher Southan - Bishops Stortford, GB
Conrad G Chapman - Orpington, GB
Joanne R Evans - Bishops Stortford, GB
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
SmithKline Beecham plc - Brentford
SmithKline Beecham plc - Brentford
International Classification:
C12N 950, C12N 1500, C12N 120, C07H 2104
US Classification:
435219
Abstract:
ASP1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP1 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimers's Disease, cancer, and melanoma, among others, and diagnostic assays for such conditions.
Asp1
US Patent:
6162630, Dec 19, 2000
Filed:
Nov 4, 1999
Appl. No.:
9/434427
Inventors:
David J Powell - Radnor PA
Christopher Southan - Bishop Stortford, GB
Conrad G Chapman - Orpington, GB
Joanne R Evans - Herts, GB
Christopher Southan - Bishop Stortford, GB
Conrad G Chapman - Orpington, GB
Joanne R Evans - Herts, GB
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
SmithKline Beecham plc - Middlesex
SmithKline Beecham plc - Middlesex
International Classification:
C12N 950, C07K 100
US Classification:
435219
Abstract:
ASP1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP1 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimers's Disease, cancer, and melanoma, among others, and diagnostic assays for such conditions.
Reductase
US Patent:
2002015, Oct 24, 2002
Filed:
Feb 7, 2001
Appl. No.:
09/778319
Inventors:
David Powell - Radnor PA, US
David Tew - Audubon PA, US
David Tew - Audubon PA, US
International Classification:
C12N009/00, C07H021/04, C12N005/06, C07K016/40
US Classification:
435/183000, 435/325000, 435/320100, 435/455000, 536/023200, 530/388260
Abstract:
Novel reductase polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing novel reductase polypeptides and polynucleotides in diagnostic assays.