Inventors:
Brian Aquila - Marlborough MA, US
Donald Cook - Derry NH, US
Leslie Dakin - Natick MA, US
Stephanos Ioannidis - Watertown MA, US
Paul Lyne - Arlington MA, US
David Scott - Somerville MA, US
Xiaolan Zheng - Waltham MA, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/427, C07D 277/46, A61K 31/426, A61P 35/00, C07D 417/02
Abstract:
The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.