Inventors:
Kenneth R. Lutchen - Framingham MA
David W. Kaczka - South Boston MA
Bela Suki - Newton Upper Falls MA
Assignee:
Trustees of Boston University - Boston MA
International Classification:
A61M 1600
US Classification:
12820421, 12820418, 12820024
Abstract:
A novel ventilator waveform having an enhanced inspiratory flow pattern is ideally suited for determining an effective âinspiratory impedanceâ in ventilator-dependent patients, and/or patients with severe obstruction resulting in expiratory flow-limitation. This waveform is referred to herein as the âEnhanced Ventilator Waveformâ (EVW). The EVW maintains ventilatory support while simultaneously providing an accurate and sensible assessment of the mechanical status of the lungs or total respiratory system. The EVW technique of the present invention ensures that normal (tidal) volume levels are delivered during each inspiration, and that expiration remains passive. Furthermore, accurate estimation of lung resistance and elastance is established for several frequencies surrounding the primary ventilator breathing rate. From the resistance and elastance data, the mean level and structural distribution of airway versus tissue constriction conditions in the lung can be inferred. Additionally, the distribution of delivered gas is more uniform (i.