Inventors:
David W. Andrews - Philadelphia PA
Renato L. Baserga - Ardmore PA
Mariana Resnicoff - Buenos Aires, AR
David Abraham - Wynnewood PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
A61K 3512
US Classification:
424573, 424572, 424422, 424424, 424 931, 536 231, 514 44, 4353201, 435325
Abstract:
A method of inducing resistance to or regression of tumor growth comprising placing tumor cells in culture in vitro or ex vivo supplemented with a pro-apoptotic agent for a period of time, transferring the tumor cells into a diffusion chamber, thereby producing a cell-containing chamber, inserting the chamber into a human for a therapeutically effective time, thereby inducing resistance to or regression of tumor growth.