David T Fikstad
Land Surveyors in Salt Lake City, UT
License number
Utah 181670-9925
Issued Date
Jan 1, 1911
Expiration Date
Dec 31, 1999
Category
Engineer/Land Surveyor
Type
Engineer in Training - Obsolete
Address
Address
Salt Lake City, UT
Personal information
See more information about David T Fikstad at radaris.comName
Address
Phone
156 Lincoln St, Salt Lake City, UT 84102
726 Green St, Salt Lake City, UT 84102
Professional information
Method Of Making Pressure Sensitive Adhesive Matrix Patches For Transdermal Drug Delivery Using Hydrophilic Salts Of Drugs And Hydrophobic Pressure Sensitive Adhesive Dispersions
US Patent:
6365178, Apr 2, 2002
Filed:
Jan 17, 2001
Appl. No.:
09/764040
Inventors:
Srinivasan Venkateshwaran - Salt Lake City UT
David Fikstad - Salt Lake City UT
Charles D. Ebert - Salt Lake City UT
David Fikstad - Salt Lake City UT
Charles D. Ebert - Salt Lake City UT
Assignee:
Watson Pharmaceuticals, Inc. - Corona CA
International Classification:
A61K 970
US Classification:
424449, 424447, 424448
Abstract:
A method of making a pressure sensitive matrix patch for transdermal delivery of a drug is disclosed. The method includes the steps of dissolving a hydrophilic salt form of the drug in the water phase of an aqueous dispersion of a hydrophobic pressure sensitive adhesive, casting the resulting mixture as a thin film, and evaporating the water. The physical stability of the drug in the film is excellent, and crystallization of the drug is inhibited. A method of increasing the transdermal flux of an acidic drug is also disclosed.
Pharmaceutical Compositions And Dosage Forms For Administration Of Hydrophobic Drugs
US Patent:
2003023, Dec 25, 2003
Filed:
May 22, 2003
Appl. No.:
10/444935
Inventors:
Mahesh Patel - Salt Lake City UT, US
David Fikstad - Salt Lake City UT, US
Huiping Zhang - Salt Lake City UT, US
Chandrashekar Gilyar - Salt Lake City UT, US
David Fikstad - Salt Lake City UT, US
Huiping Zhang - Salt Lake City UT, US
Chandrashekar Gilyar - Salt Lake City UT, US
International Classification:
A61K031/56, A61K031/355, A61K031/122
US Classification:
514/171000, 514/458000, 514/682000
Abstract:
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs, particularly steroids, are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, preferably a vitamin E substance; and a surfactant. The synergistic effect between the hydrophobic drug and the vitamin E substance results in a pharmaceutical formulation with improved dispersion of both the active agent and the solubilizer. As a result of the improved dispersion, the pharamaceutical composition has improved bioavailability upon administration. Methods of improving the bioavailability of hydrophobic drugs administered to a patient are also provided.
Fatty Acid Esters Of Glycolic Acid And Its Salts
US Patent:
5912009, Jun 15, 1999
Filed:
Oct 29, 1997
Appl. No.:
8/959944
Inventors:
Srinivasan Venkateshwaran - Salt Lake City UT
David Fikstad - Salt Lake City UT
Sonal R. Patel - Sandy UT
David Fikstad - Salt Lake City UT
Sonal R. Patel - Sandy UT
Assignee:
TheraTech, Inc. - Salt Lake City UT
International Classification:
A61F 1302
US Classification:
424448
Abstract:
A transdermal drug delivery system which enhances the delivery of the drug comprises a composition containing, as an enhancer, one or more C. sub. 6 to C. sub. 22 fatty acid esters of glycolic acid and its salts. These compositions are made up of a safe and effective amount of an active pharmaceutical permeant contained in a penetration-enhancing vehicle comprising, 0. 25 to 50% w. of the fatty acid glycolic acid ester enhancer in a suitable carrier vehicle. These fatty acid glycolic acid ester enhancers may be used in various carrier vehicles to enhance the transdermal delivery of active permeants in either free form or used in an occlusive device, particularly in a transdermal patch in matrix or reservoir form. When used in matrix patch form, the fatty acid glycolic acid ester enhancers and permeants are incorporated into a biocompatible adhesive. When used in a reservoir type patch, the permeant and fatty acid glycolic acid ester enhancers are incorporated into a carrier fluid of controlled viscosity such as a gel or ointment preferably containing a lower alkanol and water.
Anti-Inflammatory And Analgesic Compositions And Related Methods
US Patent:
2007028, Dec 6, 2007
Filed:
Jun 6, 2006
Appl. No.:
11/448597
Inventors:
Shanthakumar Tyavanagimatt - Salt Lake City UT, US
David Fikstad - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
David Fikstad - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
International Classification:
A61K 31/5415
US Classification:
5142265
Abstract:
Methods and compositions for delivering a meloxicam compound are disclosed and described. In one aspect, a method may include perorally administering to a subject a therapeutically effective amount of a meloxicam compound that provides a meloxicam plasma concentration within 1 hour which is at least about 40% of the maximum plasma concentration attained by the formulation. In another aspect, a composition may include a therapeutically effective amount of a meloxicam compound in a pharmaceutically acceptable carrier including at least one of an alkalizer or a solubilizer, with the meloxicam compound having a solubility in the carrier that is greater than about 1.0 mg/gm.
Pharmaceutical Compositions With Synchronized Solubilizer Release
US Patent:
2006000, Jan 5, 2006
Filed:
May 4, 2005
Appl. No.:
11/122788
Inventors:
David Fikstad - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
International Classification:
A61K 31/724, A61K 31/401, A61K 31/366, A61K 9/22, A61K 31/355, A61K 31/225
US Classification:
424468000, 514423000, 514460000, 514458000, 514058000, 514548000
Abstract:
Pharmaceutical compositions with synchronized solubilizer release as well as various methods associated therewith, are disclosed and described. More specifically, the aqueous solubility of a drug is enhanced by synchronized release of a solubilizer.
Pharmaceutical Compositions With Synchronized Solubilizer Release
US Patent:
2005009, May 5, 2005
Filed:
Nov 3, 2003
Appl. No.:
10/700838
Inventors:
David Fikstad - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
International Classification:
A61K031/724, A61K031/426, A61K031/355
US Classification:
514369000, 514423000, 514469000, 514458000, 514058000
Abstract:
Pharmaceutical compositions with synchronized solubilizer release as well as various methods associated therewith, are disclosed and described. More specifically, the aqueous solubility of a drug is enhanced by synchronized release of a solubilizer.
Fatty Acid Esters Of Lactic Acid Salts As Permeation Enhancers
US Patent:
5952000, Sep 14, 1999
Filed:
Oct 29, 1997
Appl. No.:
8/959946
Inventors:
Srinivasan Venkateshwaran - Salt Lake City UT
David Fikstad - Salt Lake City UT
Sonal R. Patel - Sandy UT
David Fikstad - Salt Lake City UT
Sonal R. Patel - Sandy UT
Assignee:
TheraTech, Inc. - Salt Lake City UT
International Classification:
A61F 1302
US Classification:
424448
Abstract:
A transdermal drug delivery system which enhances the delivery of the drug comprises a composition containing, as an enhancer, one or more C. sub. 6 to C. sub. 22 fatty acid esters of a lactic acid salt. These compositions are made up of a safe and effective amount of an active pharmaceutical permeant contained in a penetration-enhancing vehicle comprising, 0. 25 to 50% w. of the fatty acid ester of a lactic acid salt enhancer in a suitable pressure sensitive adhesive carrier vehicle formed from and aqueous emulsion based pressure sensitive adhesive.
Pharmaceutical Compositions With Synchronized Solubilizer Release
US Patent:
2005009, May 5, 2005
Filed:
Jan 23, 2004
Appl. No.:
10/764016
Inventors:
David Fikstad - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
Srinivasan Venkateshwaran - Salt Lake City UT, US
Chandrashekar Giliyar - Salt Lake City UT, US
Mahesh Patel - Salt Lake City UT, US
International Classification:
A61K031/724, A61K031/426, A61K031/401, A61K031/366
US Classification:
514058000, 514369000, 514423000, 514460000, 514548000, 514458000, 514571000
Abstract:
Pharmaceutical compositions with synchronized solubilizer release as well as various methods associated therewith, are disclosed and described. More specifically, the aqueous solubility of a drug is enhanced by synchronized release of a solubilizer.
Transdermal Drug Delivery Systems Containing Quaternary Ammonium Salts And Methods Of Using The Same
US Patent:
2003009, May 15, 2003
Filed:
Mar 21, 2002
Appl. No.:
10/105032
Inventors:
David Fikstad - Salt Lake City UT, US
Charles Ebert - Yorba Linda CA, US
Srinivasan Venkateshwaran - So. Burlington VT, US
Lawrence Nilssen - Bountiful UT, US
Charles Ebert - Yorba Linda CA, US
Srinivasan Venkateshwaran - So. Burlington VT, US
Lawrence Nilssen - Bountiful UT, US
International Classification:
A61K009/70
US Classification:
424/449000
Abstract:
A transdermal drug delivery system is disclosed, which includes a polymer, a drug and an amount of a quaternary ammonium salt that is sufficient to act as a penetration enhancer. The quaternary ammonium salt may also be present in an amount sufficient to act as an irritation reducer. Further, the transdermal drug delivery system may also contain a co-enhancer, which provides a synergistic skin permeation enhancing effect when combined with the quaternary ammonium salt. A method for enhancing the transdermal delivery of a drug is also disclosed.
Pressure Sensitive Adhesive Matrix Patches For Transdermal Delivery Of Salts Of Pharmaceutical Agents
US Patent:
5985317, Nov 16, 1999
Filed:
Sep 6, 1996
Appl. No.:
8/706624
Inventors:
Srinivasan Venkateshwaran - Salt Lake City UT
David Fikstad - Salt Lake City UT
Charles D. Ebert - Salt Lake City UT
David Fikstad - Salt Lake City UT
Charles D. Ebert - Salt Lake City UT
Assignee:
TheraTech, Inc. - Salt Lake City UT
International Classification:
A61L 1516
US Classification:
424449
Abstract:
A method of transdermally or transmucosally delivering a hydrophilic salt form of a drug with a water-based pressure sensitive hydrophobic adhesive matrix patch optionally containing a permeation enhancer is disclosed. A matrix patch comprising a water-based pressure sensitive hydrophobic adhesive, a hydrophilic salt form of a drug, and optionally a permeation enhancer for transdermal or transmucosal delivery of the hydrophilic salt form of the drug is also disclosed.