Inventors:
David Geliebter - Franklin Lakes NJ, US
David Solomon - Brooklyn NY, US
International Classification:
A61K045/00, A61K031/5415, A61K031/52, A61K031/517
US Classification:
424093700, 514263220, 514224200, 514266210, 514263400
Abstract:
The present invention relates to ex vivo methods for preserving/maintaining blood vessels that are to be used as vascular grafts by specifically inhibiting Type I and/or Type II phosphodiesterases. The present invention also relates to compositions comprising a specific inhibitor of a Type I and/or Type II phosphodiesterase for use in the methods of the invention.