DAVID S WOLF, M.D.
Osteopathic Medicine at Sunset Blvd, Houston, TX

6673597, Jan 6, 2004

Feb 28, 2001

09/798854

David A. Wolf - Houston TX
Thomas J. Goodwin - Friendswood TX

The United States of America as represented by the Administrator of the National Aeronautics and Space Administration - Washington DC

C12M 110

4352982, 4352991

The present invention provides systems for growing two or three dimensional mammalian cells within a culture medium facilitated by an electromagnetic field, and preferably, a time varying electromagnetic field. The cells and culture medium are contained within a fixed or rotating culture vessel, and the electromagnetic field is emitted from at least one electrode. In one embodiment, the electrode is spaced from the vessel. The invention further provides methods to promote neural tissue regeneration by means of culturing the neural cells in the claimed system. In one embodiment, neuronal cells are grown within longitudinally extending tissue strands extending axially along and within electrodes comprising electrically conductive channels or guides through which a time varying electrical current is conducted, the conductive channels being positioned within a culture medium.

2008009, Apr 24, 2008

Oct 18, 2007

11/874410

Philip MUCCIO - Columbus OH, US
Robert DENNIS - Chapel Hill NC, US
David WOLF - Houston TX, US
Marc LABBE - Houston TX, US

A61N 1/34, A61N 1/00, A61N 1/36

607003000, 607046000, 607050000

A system for stimulating tissue to relieve pain and repair and/or regenerate tissue comprising a garment that has an electrode, a programmable electrical stimulation device, a time varying electromagnetic field generator, and a source that provides an electrical current. Also provided is a method wherein the electrode provides the user with a stimulating current and the time varying electromagnetic field provides the user with a time varying electromagnetic field either simultaneously, alternating, and/or sequentially.

2009008, Mar 26, 2009

Sep 24, 2007

11/859991

Robert G. DENNIS - Raleigh NC, US
David A. WOLF - Houston TX, US
Donnie RUDD - Sugar Land TX, US

A61N 2/02, A61K 35/12

600 13, 424 937

An osteo or tissue healing kit and method of promoting the healing of compromised bone or tissue in a living mammal. The osteo or tissue healing device of the kit includes a magnetic field emitter and a controlling circuit, and at least one stem cell. The method of using the osteo or tissue healing kit includes placing at least one stem cell within the compromised bone or tissue and applying a time variant magnetic field.

5026650, Jun 25, 1991

Jun 30, 1988

7/213558

Ray P. Schwarz - League City TX
David A. Wolf - Houston TX
Tinh T. Trinh - Houston TX

The United States of Amercia as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

C12M 302

435286

A bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through the membrane and disbursed into the fluid medium along the length of the membrane.

5153133, Oct 6, 1992

Apr 15, 1991

7/687605

Ray P. Schwarz - League City TX
David A. Wolf - Houston TX
Tinh T. Trinh - Houston TX

The United States of America as represented by the Administrator,
National Aeronautics and Space Administration - Washington DC

C12N 502

43524024

A bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through the membrane and disbursed into the fluid medium along the length of the membrane.