Inventors:
Helen Vivian Hsieh - Durham NC, US
J. Bruce Pitner - Durham NC, US
Terry J. Amiss - Cary NC, US
Colleen M. Nycz - Raleigh NC, US
Douglas B. Sherman - Durham NC, US
David J. Wright - Madison WI, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
C07K 14/00, A61K 38/00
Abstract:
The invention is directed to compositions of mutated binding proteins containing reporter groups, analyte biosensor devices derived therefrom, and their use as analyte biosensors both in vitro and in vivo.