DAVID NICHOLAS PHELPS
Pilots at Rosewood Ave, Louisville, KY

2004014, Jul 29, 2004

Oct 9, 2003

10/681323

Scott Wolf - Minneapolis MN, US
Greg Furnish - Louisville KY, US
Todd Hall - Goshen KY, US
David Phelps - Louisville KY, US
Peter Wilk - New York NY, US
Nancy Briefs - Nashua NH, US
William Santamore - Medford NJ, US
Daniel Burkhoff - Tenafly NJ, US
Simon Furnish - Louisville KY, US
Stephen Evans - Westford MA, US
Roger Kamm - Weston MA, US
Richard Renad - San Jose CA, US
Gerald Melsky - Lexington MA, US
Eun Shim - Kumi, KR

Percardia, Inc.

A61M005/00, A61F011/00

604/008000, 606/108000

Left ventricular conduits and related methods are disclosed for achieving bypass of a partially or completely occluded coronary artery. More broadly, conduits for allowing communication of bodily fluids from one portion of a patient's body to another and related methods are disclosed, including conduits for forming a blood flow path from a chamber of the heart to a vessel or from one vessel to another. In other embodiments, the conduits achieve a coronary artery bypass by allowing blood communication between the left ventricle and the coronary artery or between a proximal portion of the coronary artery and a distal portion of the coronary artery. The conduits may be placed completely through the heart wall or extend only partially therein. Conduits may take on a variety of configurations for allowing the control of blood flow therethrough, including curved or tapered shapes. The conduits may also follow a variety of paths, including direct transmyocardial communication between the left ventricle and the coronary artery, or through the myocardium and into the intrapericardial space and then into the coronary artery. The conduits may be implanted through a variety of methods, including minimally invasive techniques. Also disclosed are various preferred embodiments of medical devices and related methods for implanting the conduits including rigid delivery rods for penetrating bodily tissue. The delivery rods may be solid, thus being trocar-like, or hollow to form a self-implantable conduit. Other preferred rod embodiments may have the conduits mounted thereon and take the form of a stylet or the like. The conduits may be one-piece, continuous conduits or made up of a number of plural sections joined together. Disclosures of various anastomosis devices are provided.

6261304, Jul 17, 2001

Aug 4, 1999

9/368868

Todd A. Hall - Goshen KY
Greg R. Furnish - Louisville KY
Simon M. Furnish - Louisville KY
Scott J. Wolf - Minneapolis MN
Peter J. Wilk - New York NY
David Y. Phelps - Louisville KY

Percardia, Inc. - Merrimack NH

A61M 2900

606194

Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium.

6881199, Apr 19, 2005

Apr 10, 2001

09/828794

Peter J. Wilk - New York NY, US
David Y. Phelps - Louisville KY, US
Scott J. Wolf - Minneapolis MN, US

Percardia, Inc. - Nashua NH

A61M005/00, A61B017/08, A61F002/06, A61F002/04

604 9, 606153, 623 124, 623 2368

A method of flowing blood from a heart chamber to a coronary vessel includes providing a conduit with a first end and second end, providing the conduit within a heart wall such that the first end of the conduit is open towards the heart chamber and the second end is open towards the blood vessel, and during diastole, restricting a flow of blood from the coronary vessel to the heart chamber via the natural valve.

8597226, Dec 3, 2013

Jun 12, 2012

13/494589

Peter J. Wilk - New York NY, US
David Y. Phelps - Louisville KY, US
Scott J. Wolf - Minneapolis MN, US

JenaValve Technology, Inc. - Wilmington DE

A61M 5/00, A61B 17/08, A61F 2/06, A61F 2/04

604 9, 606153, 623 124, 623 2368

Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.

2007014, Jun 21, 2007

Sep 1, 2006

11/469571

David Phelps - Louisville KY, US

B01J 19/00

422130000

An automated synthesizer is disclosed in which the reaction wells are moved by a carrier into alignment with stationary fluid delivery stations that are in communication with a source of reactants and/or wash solutions. In an alternate embodiment the delivery stations are moved into alignment with stationary reaction wells. A method for synthesizing chemical compounds employing the synthesizer is disclosed.

6290728, Sep 18, 2001

Aug 4, 1999

9/369048

David Y. Phelps - Louisville KY
Greg R. Furnish - Louisville KY
Todd A. Hall - Goshen KY
Mark Griffin - Louisville KY
Scott J. Wolf - Minneapolis MN
Peter J. Wilk - New York NY
Jay Schmelter - Plymouth MN
Simon Furnish - Louisville KY

Percardia, Inc. - Nashua NH

A61F 206

623 237

A conduit is provided to provide a bypass around a blockage in the coronary artery. The conduit is adapted to be positioned in the myocardium or heart wall to provide a passage for blood to flow between a chamber of the heart such as the left ventricle and the coronary artery, distal to the blockage. The stent is self-expanding or uses a balloon to expand the stent in the heart wall. Various attachment means are provided to anchor the stent and prevent its migration.

7704222, Apr 27, 2010

Aug 30, 2004

10/928190

Peter J. Wilk - New York NY, US
David Y. Phelps - Louisville KY, US
Scott J. Wolf - Minneapolis MN, US

JenaValve Technology, Inc. - Wilmington DE

A61M 5/00, A61B 17/08, A61F 2/06, A61F 2/04

604 9, 606153, 623 124, 623 2368

Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.

2007011, May 17, 2007

Mar 10, 2006

11/372818

David Phelps - Louisville KY, US

B01J 19/00

422130000

An automated synthesizer is disclosed in which the reaction wells are moved by a carousel into alignment with stationary nozzles that are in communication with the source of reactants and/or washing solutions. By moving the wells rather than moving the nozzles for the delivery of reagents and washing solutions, the amount of time required to introduce reagent is substantially reduced.

6221048, Apr 24, 2001

Oct 27, 1998

9/179708

David Y. Phelps - Louisville KY

A61M 5178

60416412

A needle device for the delivery of medicaments, insuflation or other medical devices, having a reciprocable needle sensitive to lack of resistance, whereupon such needle retracts, permitting a cannula therewith to provide access to the penetrated body.