DAVID NEAL LIEBOWITZ
Medical Practice in Seattle, WA
License number
Pennsylvania MD067547L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Seattle, WA 98110
Pennsylvania
Pennsylvania
Professional information
Methods Of Using Flt3-Ligand In Immunization Protocols
US Patent:
2004002, Feb 5, 2004
Filed:
Mar 26, 2003
Appl. No.:
10/401364
Inventors:
Hilary McKenna - Seattle WA, US
David Liebowitz - Seattle WA, US
Charles Maliszewski - Seattle WA, US
David Liebowitz - Seattle WA, US
Charles Maliszewski - Seattle WA, US
International Classification:
A61K039/00, A61K038/21, A61K038/19, A61K038/20
US Classification:
424/085100, 424/085700, 424/185100, 424/085200
Abstract:
The present invention relates to methods of using Flt3-ligand (Flt3-L) in immunization protocols to enhance immune responses against vaccine antigens. Embodiments include administering Flt3-ligand prior to immunizing a subject with a vaccine, wherein the vaccine comprises at least one antigen formulated in one or more adjuvants. Methods of treating and preventing disease and infection using Flt3-ligand immunization protocols are also provided. Methods of using Flt3-ligand immunization protocols for in vivo evaluation of antigens and adjuvants are also provided.