Inventors:
Catherine Baty - Pittsburgh PA, US
Robert Ferrell - Pittsburgh PA, US
David Finegold - Pittsburgh PA, US
Assignee:
University of Pittsburgh-Of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
C12Q 1/68
Abstract:
Methods are provided for identifying risk of developing lymphedema, including primary and secondary edema. The methods comprise identifying the presence in a biological sample of a polymorphism in one or more of GJA4, GJA5 and GJC2, resulting in a functional mutation of one or more of connixin 37 (Cx37), Cx40 or Cx47.