DR. DAVID MARSHALL SHAMES, M.D.
Medical Practice at Claremont Blvd, Berkeley, CA
License number
California G18387
Category
Medical Practice
Type
Nuclear Medicine
Address
Address
2737 Claremont Blvd, Berkeley, CA 94705
Phone
(510) 841-6278
Professional information
Dr. David M Shames, Berkeley CA - MD (Doctor of Medicine)
Specialties:
Nuclear Medicine
Address:
SHAMES, DAVID M MD
2737 Claremont Blvd, Berkeley 94705
(510) 841-1679 (Phone)
2737 Claremont Blvd, Berkeley 94705
(510) 841-1679 (Phone)
Certifications:
Nuclear Medicine, 1972
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Yale University
Graduated: 1965
Yale University
Graduated: 1965
Imaging Method For The Grading Of Tumors
US Patent:
6009342, Dec 28, 1999
Filed:
Feb 27, 1998
Appl. No.:
9/032357
Inventors:
Robert C. Brasch - Mill Valley CA
Heike E. Daldrup - Munster, DE
David M. Shames - Berkeley CA
Heike E. Daldrup - Munster, DE
David M. Shames - Berkeley CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61B 5055
US Classification:
600420
Abstract:
The endothelial integrity of microvessels is disturbed in malignant tumors. We invented a method wherein we used MRI to define tumor microvascular permeabilities and correlated these permeabilities with histologic grade in tumors. Using macromolecular MRI contrast medium, we discovered tumor microvascular permeability values were significantly lower in benign tumors than in carcinomas. In addition, we found that the microvascular permeability values demonstrated a strong correlation with the histologic grade of carcinomas as determined by the Scarff-Bloom-Richardson grading system.