DAVID KENNETH GIFFORD
Pilots at Pigeon Hl Rd, Cherry Brook, MA

7191447, Mar 13, 2007

Aug 25, 2000

09/645933

John R. Ellis - Woodside CA, US
David K. Gifford - Weston MA, US
G. Winfield Treese - Newton MA, US

Soverain Software LLC - Chicago IL

G06F 13/00

719310

The invention features various techniques for managing transfers of information in public packet switched communications networks. In one aspect, the invention provides a system for identifying updated items of network-based information, such as pages, to users in a network. A master server receives the data from each of a plurality of network servers and merges them into one or more master logs. The logs have entries that pertaining to creation of or changing of pages of information. Another aspect of the invention features a system for implementing security protocols. A proxy server translates links from a protocol incompatible with the network tool to a protocol compatible with the network tool and back-translates the link. Another aspect of the invention features a system for managing authenticating credentials of a user. A proxy server manages a user's authenticating credentials automatically on behalf of the user.

6199051, Mar 6, 2001

Mar 2, 1998

9/033255

David K. Gifford - Weston MA

Open Market, Inc. - Cambridge MA

G06F 1760

705 75

A complete system for the purchasing of goods or information over a computer network is presented. Merchant computers on the network maintain databases of digital advertisements that are accessed by buyer computers. In response to user inquiries, buyer computers retrieve and display digital advertisements from merchant computers. A digital advertisement can further include a program that is interpreted by a buyer's computer. The buyer computers include a means for a user to purchase the product described by a digital advertisement. If a user has not specified a means of payment at the time of purchase, it can be requested after a purchase transaction is initiated. A network payment system performs payment order authorization in a network with untrusted switching, transmission, and host components. Payment orders are backed by accounts in an external financial system network, and the payment system obtains account authorizations from this external network in real-time. Payment orders are signed with authenticators that can be based on any combination of a secret function of the payment order parameters, a single-use transaction identifier, or a specified network address.

5750335, May 12, 1998

Apr 22, 1993

8/052157

David K. Gifford - Weston MA

Massachusetts Institute of Technology - Cambridge MA

C12Q 168, C12P 1934, C07K 14195, C07K 1700

435 6

Disclosed is a method of genetic screening for a nucleotide variation, the method including the steps of (A) providing a mixture of nucleic acids comprising heteroduplex nucleic acids and excess homoduplex nucleic acids, wherein each said heteroduplex comprises a test nucleic acid strand isolated from an organism and a reference nucleic acid strand, each said heteroduplex also comprising a mismatched nucleotide pair, wherein said excess homoduplex nucleic acids are generated by reannealing of a first test or reference nucleic acid strand with a fully complementary second test or reference nucleic acid strand; (B) subjecting said mixture to a mismatch binding protein under conditions which promote binding to form a heteroduplex/binding protein complex; and C) detecting the presence of said mismatched nucleotide pair as an indication of the presence of genetic variation between said test and reference nucleic acids.

7124092, Oct 17, 2006

Jul 3, 2001

09/897407

David K. Gifford - Weston MA, US

Soverain Software LLC - Chicago IL

G06Q 30/00

705 14

The present invention relates to techniques for controlling transfers of information in computer networks. One technique involves transmitting from a server computer to a client computer a document containing a channel object corresponding to a communication service, and storing an access ticket that indicates that a user of the client computer permits the information source computer to communicate with the user over a specified channel. Another technique involves transmitting smart digital offers based on information such as coupons and purchasing histories stored at the computer receiving the offer. Another technique involves transmitting from a server computer to a client computer a request for a user's personal profile information, and activating a client avatar that compares the request for personal profile information with a security profile of the user limiting access to personal profile information. Another technique involves transmitting from a server computer to a client computer a document containing an embedded link, activating the embedded link at the client computer and recording activation of the embedded link in a metering log.

6205437, Mar 20, 2001

Mar 2, 1998

9/032852

David K. Gifford - Weston MA

Open Market, Inc. - Cambridge MA

G06F 1760

705 75

A complete system for the purchasing of goods or information over a computer network is presented. Merchant computers on the network maintain databases of digital advertisements that are accessed by buyer computers. In response to user inquiries, buyer computers retrieve and display digital advertisements from merchant computers. A digital advertisement can further include a program that is interpreted by a buyer's computer. The buyer computers include a means for a user to purchase the product described by a digital advertisement. If a user has not specified a means of payment at the time of purchase, it can be requested after a purchase transaction is initiated. A network payment system performs payment order authorization in a network with untrusted switching, transmission, and host components. Payment orders are backed by accounts in an external financial system network, and the payment system obtains account authorizations from this external network in real-time. Payment orders are signed with authenticators that can be based on any combination of a secret function of the payment order parameters, a single-use transaction identifier, or a specified network address.

6195649, Feb 27, 2001

Mar 2, 1998

9/033143

David K. Gifford - Weston MA

Open Market, Inc. - Cambridge MA

G06F 1760

705 75

A complete system for the purchasing of goods or information over a computer network is presented. Merchant computers on the network maintain databases of digital advertisements that are accessed by buyer computers. In response to user inquiries, buyer computers retrieve and display digital advertisements from merchant computers. A digital advertisement can further include a program that is interpreted by a buyer's computer. The buyer computers include a means for a user to purchase the product described by a digital advertisement. If a user has not specified a means of payment at the time of purchase, it can be requested after a purchase transaction is initiated. A network payment system performs payment order authorization in a network with untrusted switching, transmission, and host components. Payment orders are backed by accounts in an external financial system network, and the payment system obtains account authorizations from this external network in real-time. Payment orders are signed with authenticators that can be based on any combination of a secret function of the payment order parameters, a single-use transaction identifier, or a specified network address.

5812776, Sep 22, 1998

Jun 7, 1995

8/486797

David K. Gifford - Weston MA

Open Market, Inc. - Burlington MA

G06F 1516, G06F 1582

39520047

This invention relates to methods for providing access to network servers. In particular, the process described in the invention includes client-server sessions over the Internet involving hypertext files. In the hypertext environment, a client views a document transmitted by a content server with a standard program known as the browser. Each hypertext document or page contains links to other hypertext pages which the user may select to traverse. The user may also access a hypertext page by providing a conventional telephone number or other descriptor. The server maps such a telephone number or descriptor to a target page identifier using a translation database and automatically directs the client to retrieve the desired page.

6242222, Jun 5, 2001

May 26, 1999

9/194936

David K. Gifford - Weston MA

Massachusetts Institute of Technology - Cambridge MA

C12Q 168, C12P 1934, C07H 2104

435 912

Methods and products are provided for the oligonucleotide-mediated polymerase-dependent mutation of template nucleic acid sequences in a programmed sequence over multiple rounds of nucleic acid synthesis. The methods employ series of mutagenic primers, all of which may be present in the initial reaction system, in which at least some of the mutagenic primers do not bind to or promote polymerization from the original template nucleic acids, but do bind to and promote polymerization from the mutagenized products of earlier rounds of the program of sequential mutagenesis. The products of the invention include mixtures of such mutagenic primers. The products and methods have applications in the biological and computational sciences.

7149771, Dec 12, 2006

Dec 28, 1999

09/472964

David K. Gifford - Weston MA, US

Cisco Technology, Inc. - San Jose CA

G06F 15/13

709203, 709226, 709235, 709240

The present invention is a new method called replica routing that automatically directs client computers that request a service to a server replica for that service. The replica chosen by replica routing is the replica that is expected to provide the best performance to the client based upon the client's location in the internetwork topology and the estimated performance of the internetwork. In addition, the system and method is designed to permit new replicas to be flexibly added without undue administrative overhead.

2010030, Dec 2, 2010

Jul 16, 2008

12/668944

David K. Gifford - Weston MA, US
P. Alexander Rolfe - Cambridge MA, US

C12Q 1/68, C40B 30/04, C07H 21/04, C40B 50/06

506 9, 435 6, 536 231, 506 26

The invention in some aspects relates to methods for measuring distances between locations in a nucleic acid. The invention relates to methods of genetic analysis useful for detecting genomic alterations. In some aspects, the invention relates to methods for detecting genomic insertions, deletions, and inversions.