Inventors:
Hunter Campbell Gillies - El Granada CA, US
Tobias Peschel - Redwood City CA, US
David J. Pizzuti - Menlo Park CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/505, A61P 7/02, A61K 31/53, A61K 31/519, A61P 9/12, A61K 31/5585, A61P 7/10, A61K 33/00
US Classification:
424613, 514274, 514250, 5142621, 514243
Abstract:
There is provided a method for treating pulmonary hypertension in a subject, comprising: administering to the subject in need thereof a daily dose of ambrisentan from 1 mg to about 15 mg, wherein the method is carried out without drug labeling instruction to monitor liver aminotransferase levels during ambrisentan treatment.