DR. DAVID J HACKAM, MD
Medical Practice in Pittsburgh, PA
License number
Pennsylvania MD419409
Category
Medical Practice
Type
Specialist
Address
Address
3705 CHILDREN'S Hospital SUITE 4A485, Pittsburgh, PA 15213
Phone
(412) 648-9673
Personal information
See more information about DAVID J HACKAM at radaris.comName
Address
Phone
5506 Aylesboro Ave, Pittsburgh, PA 15217
5506 Aylesboro Ave, Pittsburgh, PA 15217
5844 Beacon St, Pittsburgh, PA 15217
Professional information
See more information about DAVID J HACKAM at trustoria.com
Dr. David J Hackam, Pittsburgh PA - MD (Doctor of Medicine)
Dr. David J Hackam, Pittsburgh PA - MD (Doctor of Medicine)
Specialties:
Pediatric Surgery
Address:
4401 Penn Ave SUITE 6TH, Pittsburgh 15224
3705 5Th Ave SUITE 4A-485, Pittsburgh 15213
(412) 648-9673 (Phone), (412) 692-6069 (Fax)
1 Childrens Hospital Dr SUITE 7, Pittsburgh 15224
(412) 692-7280 (Phone), (412) 692-6069 (Fax)
3705 5Th Ave SUITE 4A-485, Pittsburgh 15213
(412) 648-9673 (Phone), (412) 692-6069 (Fax)
1 Childrens Hospital Dr SUITE 7, Pittsburgh 15224
(412) 692-7280 (Phone), (412) 692-6069 (Fax)
Certifications:
General Surgery, 2010, Pediatric Surgery, 2013
Awards:
Healthgrades Honor Roll
Languages:
English
David J Hackam, Sewickley PA
David J Hackam, Sewickley PA
Specialties:
Pediatrics, Surgery, Pediatric Surgery
Work:
Children's-North
2599 Wexford Bayne Rd, Sewickley, PA 15143 Womancare Center, UPMC Horizon
875 N Hermitage Rd, Hermitage, PA 16148 Children's Specialty Care Center Johnstown
865 Eisenhower Blvd, Johnstown, PA 15904 Children's Hospital of Pittsburgh of Upmc
1 Penn Ave, Pittsburgh, PA 15224 Children's Hospital of Pittsburgh
3705 5Th Ave, Pittsburgh, PA 15213 Childrens Hosp Of Pittsburgh Of Upmc
4401 Penn Ave, Pittsburgh, PA 15224 Childrens Hospital Specialty Care Center
1322 Eisenhower Blvd, Johnstown, PA 15904 UPMC Presbyterian/Shadyside
200 Lothrop St, Pittsburgh, PA 15213
2599 Wexford Bayne Rd, Sewickley, PA 15143 Womancare Center, UPMC Horizon
875 N Hermitage Rd, Hermitage, PA 16148 Children's Specialty Care Center Johnstown
865 Eisenhower Blvd, Johnstown, PA 15904 Children's Hospital of Pittsburgh of Upmc
1 Penn Ave, Pittsburgh, PA 15224 Children's Hospital of Pittsburgh
3705 5Th Ave, Pittsburgh, PA 15213 Childrens Hosp Of Pittsburgh Of Upmc
4401 Penn Ave, Pittsburgh, PA 15224 Childrens Hospital Specialty Care Center
1322 Eisenhower Blvd, Johnstown, PA 15904 UPMC Presbyterian/Shadyside
200 Lothrop St, Pittsburgh, PA 15213
Education:
Schulich School Of Medicine At The University Of Western Ontario (1992)
Gap Junction-Enhancing Agents For Treatment Of Necrotizing Enterocolitis And Inflammatory Bowel Disease
Gap Junction-Enhancing Agents For Treatment Of Necrotizing Enterocolitis And Inflammatory Bowel Disease
US Patent:
2013034, Dec 26, 2013
Filed:
Jun 19, 2013
Appl. No.:
13/921865
Inventors:
David J. Hackam - Pittsburgh PA, US
International Classification:
A61K 38/16, A61K 31/4709, A61K 31/47
US Classification:
514 213, 514311, 514314
Abstract:
The present invention relates to methods of reducing the risk of occurrence of, and/or treating, necrotizing enterocolitis (“NEC”) or inflammatory bowel disease (“IBD”) comprising administering, to a subject in need of such treatment, an effective amount of a gap junction enhancing agent (“GJEA”), for example a peptide (“GJP”) or peptide analog (“GJPA”). It is based, at least in part, on the discovery that greater functionality of gap junctions between enterocytes increases their rate of migration and reduces the severity of intestinal inflammation.
David J Hackam, Pittsburgh PA
David J Hackam, Pittsburgh PA
Specialties:
Surgeon
Address:
4401 Penn Ave, Pittsburgh, PA 15224
3705 5Th Ave, Pittsburgh, PA 15213
3705 5Th Ave, Pittsburgh, PA 15213
Board certifications:
American Board of Surgery Certification in Surgery, American Board of Surgery Sub-certificate in Pediatric Surgery (Surgery)
Use Of Toll-Like Receptor-9 Agonists, Toll-Like Receptor-4 Antagonists, And/Or Nuclear Oligomerization Domain-2 Agonists For The Treatment Or Prevention Of Toll-Like Receptor-4-Associated Disorders
Use Of Toll-Like Receptor-9 Agonists, Toll-Like Receptor-4 Antagonists, And/Or Nuclear Oligomerization Domain-2 Agonists For The Treatment Or Prevention Of Toll-Like Receptor-4-Associated Disorders
US Patent:
2008031, Dec 18, 2008
Filed:
Apr 17, 2008
Appl. No.:
12/104816
Inventors:
David J. Hackam - Pittsburgh PA, US
Ward M. Richardson - Pittsburgh PA, US
Steven C. Gribar - Monroeville PA, US
Alexander P. Ducruet - Pittsburgh PA, US
Ward M. Richardson - Pittsburgh PA, US
Steven C. Gribar - Monroeville PA, US
Alexander P. Ducruet - Pittsburgh PA, US
International Classification:
A61K 31/7084, A61K 39/395, A61K 38/12, A61K 38/05, A61P 31/04
US Classification:
4241301, 514 44, 514 11, 514 19
Abstract:
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
Novel Tlr4 Inhibitors For The Treatment Of Human Infectious And Inflammatory Disorders
Novel Tlr4 Inhibitors For The Treatment Of Human Infectious And Inflammatory Disorders
US Patent:
2013028, Oct 24, 2013
Filed:
Mar 22, 2013
Appl. No.:
13/848809
Inventors:
University of Pittsburgh - of the Commonwealth System of Higher Education - , US
Matthew D. Neal - Pittsburgh PA, US
David J. Hackam - Pittsburgh PA, US
Matthew D. Neal - Pittsburgh PA, US
David J. Hackam - Pittsburgh PA, US
International Classification:
A61K 31/7008, A61K 31/7034
US Classification:
514 35, 514 23, 514 53, 514 25, 536 172, 536 187
Abstract:
The present invention relates to methods of treating infectious, inflammatory and post-traumatic disorders by administering various compounds newly discovered to have TLR4 inhibitory activity. In addition to methods of treatment, the present invention further provides for pharmaceutical compositions comprising said compounds, together with a suitable pharmaceutical carrier. Because TLR4 is the most upstream receptor in the pro-inflammatory LPS signaling cascade, treatments of the invention, which inhibit or antagonize TLR4 action, may avoid the pitfalls associated with other cytokine inhibitors that act further down the pathway and accordingly play a less specific (and perhaps non-critical) role.
Use Of Toll-Like Receptor-9 Agonists, Toll-Like Receptor-4 Antagonists, And/Or Nuclear Oligomerization Domain-2 Agonists For The Treatment Of Prevention Of Toll-Like Receptor-4-Associated Disorders
Use Of Toll-Like Receptor-9 Agonists, Toll-Like Receptor-4 Antagonists, And/Or Nuclear Oligomerization Domain-2 Agonists For The Treatment Of Prevention Of Toll-Like Receptor-4-Associated Disorders
US Patent:
8518905, Aug 27, 2013
Filed:
May 1, 2012
Appl. No.:
13/461672
Inventors:
David J. Hackam - Pittsburgh PA, US
Steven C. Gribar - North Huntingdon PA, US
Steven C. Gribar - North Huntingdon PA, US
Assignee:
University of Pittsburgh-of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A61K 31/7084, A61K 38/05, A61K 38/12, A61K 39/395, A61K 31/04, C12Q 1/68
US Classification:
514 44R, 514 122, 514 24, 4241301
Abstract:
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
Use Of Toll-Like Receptor-9 Agonists
Use Of Toll-Like Receptor-9 Agonists
US Patent:
8518903, Aug 27, 2013
Filed:
May 13, 2011
Appl. No.:
13/068553
Inventors:
David J. Hackam - Pittsburgh PA, US
Assignee:
University of Pittsburgh—of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A61K 31/7084, A61K 38/05, A61K 38/12, A61K 39/395
US Classification:
514 44R, 514 122, 514 24
Abstract:
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.